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BCSCDB: Biomarkers of Cancer Stem Cells Database

Number of interactions with MCF7 is 67

INTERACTOR1 INT1_HGNC_ID INTERACTOR2 INT2_HGNC_ID INTERACTION_TYPE CSC_METHOD CANCER_TYPE HISTOLOGICAL_TYPE CELL_LINE INTERACTION_METHOD EXPRESSION_LEVEL PUBMED_ID
EGR13238SERPINE28951Protein-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assay followed by ChIP assayUp31501409
STUB111427POU5F19221Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of STUB1 followed by RT-PCRUp29511337
JUN6204ABCG274Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by EMSANA30482236
CXCR42561BAG3939RNA-Protein InteractionNALuminal A Breast CancerAdenocarcinomaMCF7RIP assay followed by RT-PCRNA28703799
FOXO33821BMI11066Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assayNA31672029
SMAD46770CD441681Protein-Gene InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assayNA28725489
FOXO13819AGO23263RNA-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7RIP assayNA30613295
MIR518843502AGO23263RNA-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7RIP assayNA30613295
ESR13467FXYD34027Protein-Protein InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Co-IP assay followed by Western BlottingNA28724549
SOX911204FXYD34027Protein-Gene InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Co-IP assayNA30482236
SRC11283FXYD34027Protein-Protein InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Co-IP assay followed by Western BlottingNA28724549
USP3720063GLI14317Protein-Protein InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Co-IP assayNA29422613
CEBPD1835IL6R6019Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by qPCRNA30482236
CEBPD1835KLF46348Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by qPCRNA30274780
VEGFA12680NRP18004Protein-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Co-IP followed by Western BlottingNA29179185
CEBPD1835POU5F19221Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by qPCRNA30206184
AGO23263PTBP310253Protein-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Co-IP assayNA29422613
CEBPD1835SOX211195Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by qPCRNA30233203
MYC7553HDAC514068Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assayNA30206184
SOX911204HDAC514068Protein-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Co-IP assayNA28724549
CEBPD1835NANOG20857Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by qPCRNA30206184
E2F13113NANOG20857Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assay followed by Western BlottingNA30482232
HSPA95244ABCG274Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of HSPA9 followed by qRT-PCRDown34249423
FOXO33821BMI11066Gene-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of FOXO3 followed by qRT-PCRDown31672029
WNT10B12775CD441681Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR34A31635CD441681miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR34A mimics followed by Luciferase Reporter assayDown29187905
MIR34A31635CD441681miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR34A mimics followed by qRT-PCRDown29187905
MIR70833654CD471682miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR708 mimics followed by Luciferase Reporter assayDown31273952
MIR21031587CDH11748miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assayDown31604679
MIR18531556E2F13113miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assay followed by RT-PCRDown31286834
MIR526B32100EPAS13374miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR526B mimics followed by Luciferase Reporter assay and qPCRDown35004266
MIR518843502FOXO13819miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assay followed by Western BlottingDown29100291
CXCR42561GLI14317Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of CXCR4 followed by qRT-PCRDown34052833
WNT10B12775HMGA25009Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
WNT10B12775INHBB6067Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
WNT10B12775JUN6204Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR65432910MEF2D6997miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR654 mimics followed by Dual Luciferase Reporter assay and qRT-PCRDown35235236
WNT10B12775MET7029Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR15031537PFN28882miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR150 mimics followed by Luciferase Reporter assay and qRT-PCRDown30628646
HSPA95244POU5F19221Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of HSPA9 followed by qRT-PCRDown34249423
CASC1528245POU5F19221Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of CASC15 followed by qRT-PCRDown35235236
MIR15031537POU5F19221miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR150 mimics followed by qRT-PCRDown30628646
FOXD2-AS144256POU5F19221Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of FOXD2-AS1 followed by qRT-PCRDown30628646
WNT10B12775PROM19454Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR130A31514RAB5B9784miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR130A mimics followed by Luciferase Reporter assay and qRT-PCRDown29746865
MIR62832884SOS111187miRNA-mRNA InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR628 mimics followe by Luciferase Reporter assayDown31604679
CASC1528245SOX211195Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of CASC15 followed by qRT-PCRDown35235236
MIR15031537SOX211195miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR150 mimics followed by qRT-PCRDown30628646
FOXD2-AS144256SOX211195Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of FOXD2-AS1 followed by qRT-PCRDown30628646
MIR30A31624SOX411200miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR30A mimics followed by Luciferase Reporter assay and qRT-PCRDown34234874
MIR124-131502STAT311364miRNA-mRNA InteractionFACs for CSC markerLuminal A Breast CancerAdenocarcinomaMCF7Dual Luciferase Reporter assay followed by qRT-PCRDown30038266
LUCAT148498TCF7L211641RNA-Protein InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7RIP assay followed by qRT-PCRDown30262865
MIR688249928TCF7L211641miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporte assayDown31736268
WNT10B12775TGFB211768Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR14031527WNT112774miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR140 mimics followed by Luciferase Reporter assayDown31690832
CASC1528245NANOG20857Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of CASC15 followed by qRT-PCRDown35235236
MIR15031537NANOG20857miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR150 mimics followed by qRT-PCRDown30628646
FOXD2-AS144256NANOG20857Gene-Gene InteractionNALuminal A Breast CancerAdenocarcinomaMCF7SiRNA mediated knockdown of FOXD2-AS1 followed by qRT-PCRDown30628646
MIR65432910CASC1528245miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR654 mimics followed by Dual Luciferase Reporter assay and qRT-PCRDown35235236
MIR688249928SPRY4-IT142394miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR6882 mimics followed by Luciferase Reporter assay and qRT-PCRDown31736268
MIR18531556LINC0051143564miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assayDown31604679
MIR15031537FOXD2-AS144256miRNA-mRNA InteractionNALuminal A Breast CancerAdenocarcinomaMCF7Transfection with MIR150 mimics followed by Luciferase Reporter assay and qRT-PCRDown30628646
TCF411634CCAT145128Protein-Gene InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7ChIP assayDown31695775
MIR148A31535CCAT145128miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assay followed by RNA pull down assayDown31695775
MIR20431582CCAT145128miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assayDown31695775
MIR21131588CCAT145128miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Luciferase Reporter assayDown31695775
MIR558243461LUCAT148498miRNA-mRNA InteractionSFALuminal A Breast CancerAdenocarcinomaMCF7Dual Luciferase Reporter assay followed by RNA pull down assayDown31690832