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BCSCDB: Biomarkers of Cancer Stem Cells Database

Number of interactions with MDA-MB-231 is 100

INTERACTOR1 INT1_HGNC_ID INTERACTOR2 INT2_HGNC_ID INTERACTION_TYPE CSC_METHOD CANCER_TYPE HISTOLOGICAL_TYPE CELL_LINE INTERACTION_METHOD EXPRESSION_LEVEL PUBMED_ID
CTNNB12514ALDH1A1402Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayUp33797754
BOP115519ALDH1A1402Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayUp33797754
TWIST112428PDGFRB8804Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Luciferase Reporter assay followed by ChIP assayUp33845139
STUB111427POU5F19221Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of STUB1 followed by RT-PCRUp29511337
CTNNB12514PROM19454Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayUp33797754
BOP115519PROM19454Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayUp33797754
SOX911204ALDH1A3409Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA30622340
CEBPD1835ATF4786Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
POU5F19221ATF4786Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
SOX211195ATF4786Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
POU5F19221ATF6791Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
SOX211195ATF6791Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
EZH23527BMI11066Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA28914785
HSP90AA15253BMI11066Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA28914785
MYC7553BMI11066Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qPCRNA28914785
SOX211195CCND11582Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA30622340
BOP115519CREBBP2348Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA33797754
ACTN4166CTNNB12514Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29197410
BOP115519CTNNB12514Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA33797754
DROSHA17904CTNNB12514Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA32859993
ZNF32614104DACH12663Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by Luciferase Reporter assayNA29187406
ZNF32614104GATA34172Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by Luciferase Reporter assayNA30021199
ZNF3213095GPER14485Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP followed by qPCRNA30478301
EZH23527HSP90AA15253Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA28914785
MYC7553HSP90AA15253Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA28914785
NFKB17794IL66018Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qPCRNA29073729
PAK18590IL66018Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qRT-PCRNA31658701
STAT311364IL66018Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qRT-PCRNA31658701
NFKB17794IL86025Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qPCRNA29073729
PAK18590JAK26192Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA31658701
VEGFA12680NRP18004Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP followed by Western BlottingNA29179185
WASF312734YBX18014Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA29262622
STUB111427POU5F19221Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29511337
GJB24284PTK29611Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA30597041
CEBPD1835SOX211195Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
FOXM13818SOX211195Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qPCRNA31296961
FOXO33821SOX211195Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by qPCRNA31296961
SOX211195SOX911204Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA30622340
PAK18590STAT311364Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA31658701
DNMT3B2979ZEB111642Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA28903350
HDAC14852ZEB111642Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA28903350
TAFAZZIN11577TEAD111714Protein-Protein InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA30479839
POU5F19221XBP112801Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA29601799
DNMT12976BCL11A13221Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assay followed by Western BlottingNA31604679
DNMT3B2979NEUROG313806Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA28903350
HDAC14852NEUROG313806Protein-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA28903350
LINC0113349447FOXP213875Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assayNA30613295
ZNF32614104KLF1718830Protein-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ChIP assay followed by Luciferase Reporter assayNA31283068
GJB24284NANOG20857Protein-Protein InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Co-IP assayNA30597041
HSPA95244ABCG274Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of HSPA9 followed by qRT-PCRDown34249423
MIR203A31581AKT1391miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR203 mimics followed by Luciferase Reporter assay and qRT-PCRDown33576006
MIR203A31581ALDH1A1402miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR203 mimics followed by Luciferase Reporter assay and qRT-PCRDown33576006
PKD3NAALDH1A1402Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR181A131590ATG5589miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR181A1 mimics followed by Dual Luciferase Reporter assay and qRT-PCRDown35029026
SOX211195AXIN2904Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of SOX2 followed by qPCRDown30622340
SOX911204AXIN2904Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of SOX9 followed by qPCRDown30622340
NFE2L27782BMI11066Gene-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of NFE2L2 followed by RT-PCRDown31672029
WNT10B12775CD441681Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR203A31581CD441681miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR203 mimics followed by Luciferase Reporter assay and qRT-PCRDown33576006
PKD3NACD441681Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR70833654CD471682miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR708 mimics followed by Luciferase Reporter assayDown31273952
MIR13931526CXCR42561miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR139 mimics followed by Dual Luciferase Reporter assay and qRT-PCRDown34070538
MIR18531556E2F13113miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Luciferase Reporter assay followed by RT-PCRDown30262865
MIR431938212E2F23114miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR4319 mimics followed by Luciferase Reporter assay and Western BlottingDown31300015
MIR526B32100EPAS13374miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR526B mimics followed by Luciferase Reporter assay and qPCRDown35004266
MIR1-131499MECOM3498miRNA-mRNA InteractionFACs for CSC markerTriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR130A mimics followed by Luciferase Reporter assay and RT-PCRDown30584335
SOX911204FZD44042Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of SOX9 followed by qPCRDown30622340
NFE2L27782GCLC4311Gene-Gene InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of NFE2L2 followed by RT-PCRDown31672029
CXCR42561GLI14317Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of CXCR4 followed by qRT-PCRDown34052833
WNT10B12775HMGA25009Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
WNT10B12775INHBB6067Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
WNT10B12775JUN6204Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
WNT10B12775MET7029Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
PKD3NANOTCH47884Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR203A31581PDK18809miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR203 mimics followed by Luciferase Reporter assay and qRT-PCRDown33576006
HSPA95244POU5F19221Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of HSPA9 followed by qRT-PCRDown34249423
LDHA6535POU5F19221Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of LDHA followed by qRT-PCRDown34178639
YAP116262POU5F19221Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of YAP1 followed by qRT-PCRDown34146553
PKD3NAPOU5F19221Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
WNT10B12775PROM19454Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
PKD3NASNAI111128Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR62832884SOS111187miRNA-mRNA InteractionFACs for CSC markerTriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR628 mimics followe by Luciferase Reporter assayDown30262865
LDHA6535SOX211195Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of LDHA followed by qRT-PCRDown34178639
YAP116262SOX211195Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231SiRNA mediated knockdown of YAP1 followed by qRT-PCRDown34146553
PKD3NASOX211195Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR30A31624SOX411200miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR30A mimics followed by Luciferase Reporter assay and qRT-PCRDown34234874
SOX211195SOX911204Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of SOX2 followed by qPCRDown30622340
MIR365A33692STAT311364miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR365A mimics followed by Luciferase Reporter assay and qPCRDown34789263
WNT10B12775TGFB211768Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of WNT10B followed by RT-PCRDown35413424
MIR14031527WNT112774miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR140 mimics followed by Luciferase Reporter assayDown31300015
MIR365A33692NOLC115608miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR365A mimics followed by Luciferase Reporter assay and qPCRDown34789263
MIR181A131590ATG2B20187miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR181A1 mimics followed by Dual Luciferase Reporter assay and qRT-PCRDown35029026
LDHA6535NANOG20857Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of LDHA followed by qRT-PCRDown34178639
MIR203A31581NANOG20857miRNA-mRNA InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR203 mimics followed by Luciferase Reporter assay and qRT-PCRDown33576006
MIR30A31624NANOG20857miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR30A mimics followed by Luciferase Reporter assay and RT-PCRDown29797562
PKD3NANANOG20857Gene-Gene InteractionNATriple Negative Breast CancerAdenocarcinomaMDA-MB-231ShRNA mediated knockdown of PKD3 followed by qPCRDown31745977
MIR34A31635RTCB26935miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR34A mimics followed by Luciferase Reporter assayDown29187905
MIR34A31635RTCB26935miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR34A mimics followed by qRT-PCRDown29187905
MIR30A31624FEZF1-AS141001miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Transfection with MIR30A mimics followed by Luciferase Reporter assay and RT-PCRDown29797562
MIR18531556LINC0051143564miRNA-mRNA InteractionSFATriple Negative Breast CancerAdenocarcinomaMDA-MB-231Luciferase Reporter assayDown30262865