Record No:1
| ACCESS NO | D107366 |
| GENE_NAME | NUP98 |
| DESCRIPTION | Nucleoporin 98 |
| ALIASES | ADIR2, NUP196, NUP96. |
| NCBI_ENTREZ_NO | 4928 |
| UNIPROT_ACCESS_NO | P52948 |
| ORGANISM | Human |
| DISEASE_PHENOTYPE | Eosinophilic Asthma, Neutrophilic Asthma |
| SAMPLE | Peripheral Blood |
| TECHNIQUES | Microarray |
| OMICS | Genomics |
| STUDY | High Throughput |
| GEO_PRIDE_ACCESS_NO | GSE106230, GSE117038 |
| COMMENTS | NUP98 was significantly up regulated in neutrophilic asthma as compared to control group. |
| REFERENCE | 30941157 |
| IMMUNITY_TERM | No |
| GO_MOLECULAR_FUNCTION | Transcription coactivator activity, RNA binding, mRNA binding, transporter activity, protein binding, nuclear localization sequence binding, peptidase activity, serine-type peptidase activity, hydrolase activity, structural constituent of nuclear pore, peptide binding, promoter-specific chromatin binding. |
| GO_BIOLOGICAL_PROCESS | Posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery, regulation of glycolytic process, DNA replication, RNA export from nucleus, mRNA export from nucleus, tRNA export from nucleus, proteolysis, protein import into nucleus, nucleocytoplasmic transport, nuclear pore organization, protein transport, viral process, protein sumoylation, poly(A)+ mRNA export from nucleus, viral transcription, telomere tethering at nuclear periphery, positive regulation of mRNA splicing via spliceosome, mRNA transport, nuclear pore complex assembly, regulation of gene silencing by miRNA, intracellular transport of virus, regulation of cellular response to heat, positive regulation of nucleic acid-templated transcription. |
| BIOGRID_INTERACTION_ID | 110982 |
| SNP_ID | - |
| DRUG_ID | - |
| STRUCTURE_ID | 203887 203888 203889 203890 203891 |
| MONOCLONAL_ANTIBODY | Anti-NUP98 antibody for Mouse, Rat, Human, African green monkey, Saccharomyces cerevisiae, Tetrahymena, Schizosaccharomyces pombe, Cat, Xenopus laevis, Caenorhabditis elegans, Drosophila melanogaster, Zebrafish. |