Browse Result
Total number of records for Atopic Dermatitis in Skin Tapings of Human in DAAB (Version-2) database: 50
| Record no | Disease | Organism | Sample | Gene Name | Techniques | Omics | Study | Comments | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | ARG1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It produces urea from L-arginine. Urea is a hygroscopic component of the natural moisturizing factor of human skin. This gene is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum . | 21211653 |
| 2 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | BLMH | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | This protein exhibited a lower expression (although not significant) in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is thought to degrade the filaggrin protein into its constitutent amino acids and these amino acids are the basic components of skin natural moisturizing factor. | 21211653 |
| 3 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | CASP14 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is required for the processing of deiminated filaggrin to produce free acids that moisturizes the skin. Mutation in this gene results in transepidermal water loss and decreased stratum corneum hydration. | 21211653 |
| 4 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | CDSN | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. This lower expression can be an indicative of inappropriate desquamation. | 21211653 |
| 5 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | DSC1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. It is a component of corneodesmosome. Corneodesmosomes bind keratins to the cellular membrane and serve to tightly attach adjacent corneocytes. Thus it acts as a skin barrier. | 21211653 |
| 6 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | DSG1 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum. This protein is related to the skin barrier. | 21211653 |
| 7 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | FLG2 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient without eczema herpeticum and nonlesional (with/without eczema) vs nonatopics. This protein is related to the skin barrier. | 21211653 |
| 8 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | GGCT | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It catalyzes the formation of pyroglutamic acid or PCA which is the most abundant cnstituent of natural moisturizing factor in the stratum corneum. | 21211653 |
| 9 | Atopic Dermatitis and Atopic Eczema | Human | Skin Tapings | TGM3 | nano-HPLC-MS/MS (ion trap) | Proteomics | High Throughput | It mediates the crosslinking of loricrin to small proline rich proteins; this complex further reinforces the cell membrane. It is expressed at significantly lower levels in lesional versus nonlesional sites of atopic dermatitis patient with/without eczema herpeticum. | 21211653 |
| 10 | Atopic Dermatitis | Human | Skin tapings | TSLP | Mass spectrometry | Proteomics. | High Throughput | Epidermal TSLP protein expression may serve as an early biomarker to predict the development of infantile Atopic Dermatitis. | 26879860 |
| 11 | Atopic Dermatitis | Human | Skin tapings (Stratum corneum), Keratinocyte culture | Gal-7 | ELISA, Western Blot | Others, Proteomics | Low Throughput | Stratum corneum Gal-7 (scGal-7) level was higher in Atopic Dermatitis patients than in healthy subjects. Gal-7 expression in keratinocytes increased after barrier disruption. The scGal-7 contents in the cheek and neck decreased in tandem with local severity scores in response to treatment. | 27028525 |
| 12 | Atopic Dermatitis | Human | Skin tapings (Stratum corneum) | HSP27 | ELISA | Others | Low Throughput | The HSP27 expression levels in the skin were elevated in patients with Atopic Dermatitis as compared to healthy subjects. | 27068691 |
| 13 | Atopic Dermatitis | Human | Skin Tapings | SERPINA3 | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 14 | Atopic Dermatitis | Human | Skin Tapings | SERPINB4 | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 15 | Atopic Dermatitis | Human | Skin Tapings | SERPINB5 | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 16 | Atopic Dermatitis | Human | Skin Tapings | IL1RN | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 17 | Atopic Dermatitis | Human | Skin Tapings | IL36RA | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 18 | Atopic Dermatitis | Human | Skin Tapings | PDI | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 19 | Atopic Dermatitis | Human | Skin Tapings | S100A4 | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 20 | Atopic Dermatitis | Human | Skin Tapings | S100A6 | LC-MS/MS | Proteomics | High Throughput | This protein is differentially expressed in Atopic Dermatitis patients as compared to healthy subjects. | 27091361 |
| 21 | Atopic Dermatitis | Human | Skin Tapings | SERPINA1 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 22 | Atopic Dermatitis | Human | Skin Tapings | SERPINB3 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 23 | Atopic Dermatitis | Human | Skin Tapings | SERPINB12 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 24 | Atopic Dermatitis | Human | Skin Tapings | S100A8 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 25 | Atopic Dermatitis | Human | Skin Tapings | S100A9 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 26 | Atopic Dermatitis | Human | Skin Tapings | S100A11 | LC-MS/MS | Proteomics | High Throughput | This protein was found as differentially abundant (via t-test) in Atopic Dermatitis patients as compared to healthy controls. | 27091361 |
| 27 | Atopic Dermatitis | Human | Skin Tapings | FLG2 | LC-MS/MS | Proteomics | High Throughput | This protein was found to be down regulated in Atopic Dermatitis skin as compared to healthy skin. | 27091361 |
| 28 | Atopic Dermatitis | Human | Skin Tapings | KRT10 | LC-MS/MS | Proteomics | High Throughput | This protein was found to be down regulated in Atopic Dermatitis skin as compared to healthy skin. | 27091361 |
| 29 | Atopic Dermatitis | Human | Skin Tapings | KRT77 | LC-MS/MS | Proteomics | High Throughput | This protein was found to be down regulated in Atopic Dermatitis skin as compared to healthy skin. | 27091361 |
| 30 | Atopic Dermatitis | Human | Skin Tapings | CASP14 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | CASP14 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 31 | Atopic Dermatitis | Human | Skin Tapings | DEFB | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | DEFB was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 32 | Atopic Dermatitis | Human | Skin Tapings | DSP | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | DSP was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 33 | Atopic Dermatitis | Human | Skin Tapings | DSG1 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | DSG1 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 34 | Atopic Dermatitis | Human | Skin Tapings | FLG | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | FLG was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 35 | Atopic Dermatitis | Human | Skin Tapings | KLK8 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | KLK8 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 36 | Atopic Dermatitis | Human | Skin Tapings | KRT10 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | KRT10 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 37 | Atopic Dermatitis | Human | Skin Tapings | S100A7 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | S100A7 was up regulated in atopic lesional skin as compared to healthy non lesional skin. S100A7 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 38 | Atopic Dermatitis | Human | Skin Tapings | S100A9 | LC-MS/MS (Selected Reaction Monitoring) | Proteomics | High Throughput | S100A9 was up regulated in atopic lesional skin as compared to healthy non lesional skin. S100A9 was found to increase in atopic non lesional skin as compared to healthy skin. | 27091361 |
| 39 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CXCL8 | Meso QuickPlex Assay | Others | High Throughput | CXCL8 was significantly higher in lesional AD skin compared to healthy and non-lesional AD skin. | 29989151 |
| 40 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CCL2 | Meso QuickPlex Assay | Others | High Throughput | CCL2 was significantly higher in lesional AD skin compared to healthy and non-lesional AD skin. | 29989151 |
| 41 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CCL22 | Meso QuickPlex Assay | Others | High Throughput | CCL22 was significantly higher in lesional AD skin compared to healthy and non-lesional AD skin. | 29989151 |
| 42 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CCL17 | Meso QuickPlex Assay | Others | High Throughput | CCL17 was significantly higher in lesional AD skin compared to healthy and non-lesional AD skin. | 29989151 |
| 43 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CCL4 | Meso QuickPlex Assay | Others | High Throughput | CCL4 was significantly reduced in non-lesional and/or lesional AD skin as compared to healthy skin. | 29989151 |
| 44 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | IL1A | Meso QuickPlex Assay | Others | High Throughput | IL1A was significantly lower in non-lesional AD skin compared to healthy skin of controls, which was even more pronounced when compared to lesional AD skin. | 29989151 |
| 45 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | IL1B | Meso QuickPlex Assay | Others | High Throughput | IL1B was significantly higher in non-lesional AD skin compared to healthy skin of controls, which was even more pronounced when compared to lesional AD skin. | 29989151 |
| 46 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | IL18 | Meso QuickPlex Assay | Others | High Throughput | IL18 was significantly higher in non-lesional AD skin compared to healthy skin of controls, which was even more pronounced when compared to lesional AD skin. | 29989151 |
| 47 | Atopic Dermatitis (AD In Children) | Human | Skin Tapings (Stratum Corneum (SC) Tape Strips) | CXCL10 | Meso QuickPlex Assay | Others | High Throughput | CXCL10 expression was significantly elevated in lesional AD skin compared to healthy skin of control. CXCL10 expression was significantly lowered in non-lesional AD skin compared to healthy skin of control. | 29989151 |
| 48 | Atopic Dermatitis | Human | Skin Tapings | OR10G7 | Whole Transcriptome Sequencing, qRT-PCR, Fluorescent Immunostaining | Transcriptomics, Genomics, Others | High Throughput, Low Throughput | OR10G7 expression was significantly increased in skin biopsy specimens from patients with Atopic Dermatitis compared with those from healthy controls. OR10G7 is expressed at significantly greater levels in undifferentiated keratinocytes from patients with Atopic Dermatitis compared with healthy controls. | 30445058 |
| 49 | Atopic Dermatitis | Human | Skin Tapings | FLG1 | Whole Transcriptome Sequencing, qRT-PCR, Fluorescent Immunostaining | Transcriptomics, Genomics, Others | High Throughput, Low Throughput | FLG1 expression is significantly reduced in atopic dermatitis patients as compared to healthy controls. | 30445058 |
| 50 | Atopic Dermatitis | Human | Skin Tapings (Stratum Corneum) | VEGF | ELISA | Others | Low Throughput | VEGF level was significantly higher in atopic dermatitis patients as compared to healthy controls. | 22042099 |