Query 'Alpha-ear domain' matched 9 Records
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Record No : 1 |
| Instance ID | 11687 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WDTW | | Bait Uniprot Accession | P97874 | | Bait Uniprot Identifier | GAK_RAT | | Bait Gene Name | Gak | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1036-1039 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction | | Interaction ID | 21687 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10887964 | | Comments | AP-2 interaction motif in rat Cyclin-G-associated kinase (Gak) that mediates binding to the alpha-ear domain of rat protein Ap2a1 |
Record No : 2 |
| Instance ID | 11688 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WAAW | | Bait Uniprot Accession | O14976 | | Bait Uniprot Identifier | GAK_HUMAN | | Bait Gene Name | GAK | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1037-1040 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21688 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955 | | Comments | AP-2 interaction motif in human Cyclin-G-associated kinase (GAK) that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 3 |
| Instance ID | 11689 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVQF | | Bait Uniprot Accession | Q8NC96 | | Bait Uniprot Identifier | NECP1_HUMAN | | Bait Gene Name | NECAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 272-275 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR; Mutational analysis | | Interaction ID | 21689 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15359277 | | Comments | The C-terminal WXXF motif of Adaptin ear-binding coat-associated protein 1 (NECAP1) that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 4 |
| Instance ID | 11690 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVQF | | Bait Uniprot Accession | Q9NVZ3 | | Bait Uniprot Identifier | NECP2_HUMAN | | Bait Gene Name | NECAP2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 260-263 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | NMR; Mutational analysis | | Interaction ID | 21690 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15359277 | | Comments | The C-terminal WXXF motif of Adaptin ear-binding coat-associated protein 2 (NECAP2) that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 5 |
| Instance ID | 11691 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVSF | | Bait Uniprot Accession | Q8WXE9 | | Bait Uniprot Identifier | STON2_HUMAN | | Bait Gene Name | STON2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 15-18 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21691 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955, 14726597 | | Comments | AP-2 interaction motif I(15-18) in human Stonin-2 that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 6 |
| Instance ID | 11692 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVQF | | Bait Uniprot Accession | Q8WXE9 | | Bait Uniprot Identifier | STON2_HUMAN | | Bait Gene Name | STON2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 102-105 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21692 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955, 14726597 | | Comments | AP-2 interaction motif II(102-105) in human Stonin-2 that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 7 |
| Instance ID | 11693 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVTF | | Bait Uniprot Accession | Q8WXE9 | | Bait Uniprot Identifier | STON2_HUMAN | | Bait Gene Name | STON2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 232-235 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21693 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955, 14726597 | | Comments | AP-2 interaction motif III(232-235) in human Stonin-2 that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin |
Record No : 8 |
| Instance ID | 11694 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WVTF | | Bait Uniprot Accession | O43426 | | Bait Uniprot Identifier | SYNJ1_HUMAN | | Bait Gene Name | SYNJ1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1481-1484 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21694 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955 | | Comments | AP-2 interaction motif in the non-neuronal 170-kDa long splice isoform of synaptojanin 1, termed SJ170, that mediates binding to the alpha-ear domain of AP-2 complex subunit alpha-1 or Alpha1-adaptin and is likely to promote efficient targeting of the polyphosphatase to the assembling clathrin lattice in non-neuronal cells |
Record No : 9 |
| Instance ID | 11695 | | Regular Expression | Wx{2,3}[FW] | | Motif Instance | WNPF | | Bait Uniprot Accession | P0C1X8 | | Bait Uniprot Identifier | AAK1_RAT | | Bait Gene Name | Aak1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 696-699 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutational analysis; Pull down(GST tag) | | Interaction ID | 21695 | | Interacting Domain | Alpha-ear domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14565955, 11877461 | | Comments | AP-2 interaction motif in rat AP2-associated protein kinase 1 (Aak1) that mediates binding to the alpha-ear domain of rat protein Ap2a1 |
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