Query 'B domain' matched 34 Records
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Record No : 1 |
| Instance ID | 10776 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LYCAE | | Bait Uniprot Accession | P35869 | | Bait Uniprot Identifier | AHR_HUMAN | | Bait Gene Name | AHR | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 331-335 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20776 | | Interacting Domain | B domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 10644764 | | Comments | The LxCxE motif in the Human dioxin aromatic hydrocarbon receptor (AHR) that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB) |
Record No : 2 |
| Instance ID | 10777 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LHCDE | | Bait Uniprot Accession | O75884 | | Bait Uniprot Identifier | RBBP9_HUMAN | | Bait Gene Name | RBBP9 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 63-67 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H; Co-IP | | Interaction ID | 20777 | | Interacting Domain | B domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9697699 | | Comments | The Rb-binding LxCxE motif in the Human RBBP9/BOG that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB) |
Record No : 3 |
| Instance ID | 10778 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LGCDE | | Bait Uniprot Accession | Q9Y6B2 | | Bait Uniprot Identifier | EID1_HUMAN | | Bait Gene Name | EID1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 178-182 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20778 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11073990 | | Comments | The Rb-binding LxCxE motif in the Human E1A-like inhibitor of differentiation 1 (EID-1) that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB) |
Record No : 4 |
| Instance ID | 10779 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LSCRE | | Bait Uniprot Accession | Q9WIJ4 | | Bait Uniprot Identifier | CLINK_FBNY1 | | Bait Gene Name | DNA-C | | Bait Organism | Faba bean necrotic yellows virus (isolate Egyptian EV1-93) (FBNYV) | | Sequence Position | 110-114 | | Critical Residues | P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20779 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10708410 | | Comments | The Rb-binding LxCxE motif in the Cell cycle link protein (Clink/DNA-C) of Faba bean necrotic yellows virus that mediates binding to the human retinoblastoma protein (RB) |
Record No : 5 |
| Instance ID | 10780 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LSCRE | | Bait Uniprot Accession | Q9WIJ4 | | Bait Uniprot Identifier | CLINK_FBNY1 | | Bait Gene Name | DNA-C | | Bait Organism | Faba bean necrotic yellows virus (isolate Egyptian EV1-93) (FBNYV) | | Sequence Position | 110-114 | | Critical Residues | P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20780 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10708410 | | Comments | The Rb-binding LxCxE motif in the Cell cycle link protein (Clink/DNA-C) of Faba bean necrotic yellows virus that mediates binding to the plant RB homologue ZmRBR1 from maize |
Record No : 6 |
| Instance ID | 10781 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LYCYE | | Bait Uniprot Accession | P03129 | | Bait Uniprot Identifier | VE7_HPV16 | | Bait Gene Name | E7 | | Bait Organism | Human papillomavirus type 16 | | Sequence Position | 22-26 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Extended conformation | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20781 | | Interacting Domain | B domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 9495340 | | Comments | The Rb-binding LxCxE motif in the human papilloma virus E7 oncoprotein that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB) |
Record No : 7 |
| Instance ID | 10782 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LKCFE | | Bait Uniprot Accession | Q99683 | | Bait Uniprot Identifier | M3K5_HUMAN | | Bait Gene Name | MAP3K5 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 916-920 | | Critical Residues | P1; P2; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag) | | Interaction ID | 20782 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15210709 | | Comments | The Rb-binding LxCxE motif in the Human apoptosis signal-regulating kinase ASK1 (MAP3K5) that mediates binding to the human retinoblastoma protein (RB) |
Record No : 8 |
| Instance ID | 10783 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LECEE | | Bait Uniprot Accession | Q99708 | | Bait Uniprot Identifier | COM1_HUMAN | | Bait Gene Name | RBBP8 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 153-157 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20783 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10449734 | | Comments | The Rb-binding LxCxE motif in the Human CtBP-interacting protein (CTIP)/ DNA endonuclease RBBP8 that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB) |
Record No : 9 |
| Instance ID | 10784 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LVCHE | | Bait Uniprot Accession | P29374 | | Bait Uniprot Identifier | ARI4A_HUMAN | | Bait Gene Name | ARID4A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 957-961 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Competition binding | | Interaction ID | 20784 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8414517 | | Comments | The Rb-binding LxCxE motif in the Human Retinoblastoma-binding protein 1 (RBP1/ARID4A) that mediates binding to the human retinoblastoma protein (RB) |
Record No : 10 |
| Instance ID | 10785 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LFCDE | | Bait Uniprot Accession | P29375 | | Bait Uniprot Identifier | KDM5A_HUMAN | | Bait Gene Name | KDM5A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1373-1377 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Competition binding | | Interaction ID | 20785 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8414517 | | Comments | The Rb-binding LxCxE motif in the Human Retinoblastoma-binding protein 2 (RBP2/KDM5A) that mediates binding to the human retinoblastoma protein (RB) |
Record No : 11 |
| Instance ID | 10786 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LVCQE | | Bait Uniprot Accession | P35251 | | Bait Uniprot Identifier | RFC1_HUMAN | | Bait Gene Name | RFC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 663-667 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20786 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11336696 | | Comments | The Rb-binding LxCxE motif in the Human Replication factor C large subunit (RFC1) that mediates binding to the human retinoblastoma protein (RB) and thereby promotes cell survival after DNA damage |
Record No : 12 |
| Instance ID | 10787 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LVCGE | | Bait Uniprot Accession | P15092 | | Bait Uniprot Identifier | IFI4_MOUSE | | Bait Gene Name | Ifi204 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 423-427 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Pull down(GST tag) | | Interaction ID | 20787 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10951565 | | Comments | The Rb-binding LxCxE motif in the mouse Interferon-inducible protein p204 (Ifi204) that mediates binding to the mouse retinoblastoma protein (Rb) |
Record No : 13 |
| Instance ID | 10788 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LVCPE | | Bait Uniprot Accession | Q13107 | | Bait Uniprot Identifier | UBP4_HUMAN | | Bait Gene Name | USP4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 459-463 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20788 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11571651 | | Comments | The Rb-binding LxCxE motif in the Human UNP/USP4, a ubiquitin-specific protease, that mediates binding to the human retinoblastoma protein (RB) |
Record No : 14 |
| Instance ID | 10789 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LACVE | | Bait Uniprot Accession | P32519 | | Bait Uniprot Identifier | ELF1_HUMAN | | Bait Gene Name | ELF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 51-55 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20789 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8493578 | | Comments | The Rb-binding LxCxE motif in the Human ETS-related transcription factor ELF1 that mediates binding to the human retinoblastoma protein (RB) |
Record No : 15 |
| Instance ID | 10790 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LTCEE | | Bait Uniprot Accession | P51531 | | Bait Uniprot Identifier | SMCA2_HUMAN | | Bait Gene Name | SMARCA2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1294-1298 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20790 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9326598 | | Comments | The Rb-binding LxCxE motif in the Human ATP-dependent helicase SMARCA2 that mediates binding to the human retinoblastoma protein (RB) to repress S-phase-inducing transcription factor E2F1, thereby preventing cells from entering S phase |
Record No : 16 |
| Instance ID | 10791 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LFCFE | | Bait Uniprot Accession | Q12931 | | Bait Uniprot Identifier | TRAP1_HUMAN | | Bait Gene Name | TRAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 525-529 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20791 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8756626 | | Comments | The Rb-binding LxCxE motif in the Human Heat shock protein HSP75/TRAP1 that mediates binding to the human retinoblastoma protein (RB) during mitosis and after heat shock, which suggests that HSP75 may act as a chaperone molecule to refold denatured RB into its native conformation |
Record No : 17 |
| Instance ID | 10792 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | IRCDE | | Bait Uniprot Accession | Q13029 | | Bait Uniprot Identifier | PRDM2_HUMAN | | Bait Gene Name | PRDM2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 310-314 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 20792 | | Interacting Domain | B domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 7538672 | | Comments | The Rb-binding LxCxE motif in the Human Zinc finger protein RIZ (PRDM2) that mediates binding to the human retinoblastoma protein (RB) suggesting a role for RIZ in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma |
Record No : 18 |
| Instance ID | 10793 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LPCAE | | Bait Uniprot Accession | P13889 | | Bait Uniprot Identifier | POLN_RUBVT | | Bait Gene Name | Not Available | | Bait Organism | Rubella virus (strain Therien) (RUBV) | | Sequence Position | 1902-1906 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20793 | | Interacting Domain | B domain | | Disease Association(s) | Rubella | | Inhibitor(s) | Unknown | | Reference(s) | 10073691 | | Comments | The Rb-binding LxCxE motif in the Rubella virus (RV)-encoded protein NSP90 that interacts with the human retinoblastoma protein (RB) and is required for efficient RV replication |
Record No : 19 |
| Instance ID | 10794 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LACSE | | Bait Uniprot Accession | Q98178 | | Bait Uniprot Identifier | Q98178_MCV1 | | Bait Gene Name | MC007L | | Bait Organism | Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) | | Sequence Position | 178-182 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 20794 | | Interacting Domain | B domain | | Disease Association(s) | Molluscum contagiosum | | Inhibitor(s) | Unknown | | Reference(s) | 18701596 | | Comments | The MC007L protein of Molluscum contagiosum virus (MCV) targets human retinoblastoma protein (RB) via a conserved LxCxE motif |
Record No : 20 |
| Instance ID | 10795 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LICHE | | Bait Uniprot Accession | Q8UYK9 | | Bait Uniprot Identifier | Q8UYK9_9GEMI | | Bait Gene Name | repA | | Bait Organism | Wheat dwarf virus - [Enkoping1] | | Sequence Position | 194-198 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20795 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8623550 | | Comments | The Rb-binding LxCxE motif in the Replication-associated protein A (repA) of Wheat dwarf virus (WDV) that mediates binding to the human retinoblastoma protein (RB) |
Record No : 21 |
| Instance ID | 10796 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LACSD | | Bait Uniprot Accession | P06726 | | Bait Uniprot Identifier | PP71_HCMVA | | Bait Gene Name | UL82 | | Bait Organism | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) | | Sequence Position | 216-220 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Western blot; Pull down; Mutation analysis | | Interaction ID | 20796 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12612064 | | Comments | The Rb-binding LxCxE motif in the Human cytomegalovirus pp71 (UL82) that mediates binding to the human retinoblastoma protein (RB) and induces DNA synthesis in quiescent cells |
Record No : 22 |
| Instance ID | 10797 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LRCHE | | Bait Uniprot Accession | O39521 | | Bait Uniprot Identifier | REPA_BEYDV | | Bait Gene Name | ORF_Name:C1 | | Bait Organism | Bean yellow dwarf virus (BeYDV) | | Sequence Position | 181-185 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20797 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10191192 | | Comments | The Rb-binding LxCxE motif in the Bean yellow dwarf virus RepA protein that mediates binding to the maize retinoblastoma protein (ZmRBR1) |
Record No : 23 |
| Instance ID | 10798 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LLCNE | | Bait Uniprot Accession | P14990 | | Bait Uniprot Identifier | REPA_MSVS | | Bait Gene Name | ORF_Name:C1 | | Bait Organism | Maize streak virus genotype A (isolate South Africa) (MSV) | | Sequence Position | 198-202 | | Critical Residues | P1; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20798 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15722542 | | Comments | The Rb-binding LxCxE motif in the Maize streak virus RepA protein that mediates binding to the maize retinoblastoma protein (ZmRBR1) |
Record No : 24 |
| Instance ID | 10799 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LYCDE | | Bait Uniprot Accession | Q9WKM8 | | Bait Uniprot Identifier | Q9WKM8_BBTV | | Bait Gene Name | Not Available | | Bait Organism | Banana bunchy top virus (BBTV) | | Sequence Position | 111-115 | | Critical Residues | P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20799 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10640570 | | Comments | The Rb-binding LxCxE motif in the Banana bunchy top virus (BBTV) DNA-5 protein that mediates binding to the human retinoblastoma protein (RB) |
Record No : 25 |
| Instance ID | 10800 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LICHE | | Bait Uniprot Accession | P06847 | | Bait Uniprot Identifier | REPA_WDVS | | Bait Gene Name | ORF_Name:C1 | | Bait Organism | Wheat dwarf virus (isolate Sweden) (WDV) | | Sequence Position | 194-198 | | Critical Residues | P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20800 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7664747 | | Comments | The Rb-binding LxCxE motif in the Wheat dwarf virus RepA protein that mediates binding to the Human Retinoblastoma-like protein 2 (RBL2) or p130RBR2 |
Record No : 26 |
| Instance ID | 10801 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LRCRE | | Bait Uniprot Accession | P16788 | | Bait Uniprot Identifier | UL97_HCMVA | | Bait Gene Name | UL97 | | Bait Organism | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) | | Sequence Position | 149-153 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20801 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18321963 | | Comments | The Rb-binding LxCxE motif (149-153) in the Human cytomegalovirus UL97 kinase that mediates binding to the human retinoblastoma protein (RB) |
Record No : 27 |
| Instance ID | 10802 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LACID | | Bait Uniprot Accession | P16788 | | Bait Uniprot Identifier | UL97_HCMVA | | Bait Gene Name | UL97 | | Bait Organism | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) | | Sequence Position | 426-430 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20802 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18321963 | | Comments | The Rb-binding LxCxE motif (426-430) in the Human cytomegalovirus UL97 kinase that mediates binding to the human retinoblastoma protein (RB) |
Record No : 28 |
| Instance ID | 10803 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LVCFE | | Bait Uniprot Accession | Q9R002 | | Bait Uniprot Identifier | IFI2_MOUSE | | Bait Gene Name | Ifi202 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 416-420 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag); Mutation analysis | | Interaction ID | 20803 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7890747 | | Comments | The Rb-binding LxCxE motif in the murine Interferon-inducible protein p202 that mediates binding to the mouse retinoblastoma protein (Rb) |
Record No : 29 |
| Instance ID | 10804 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LRCHE | | Bait Uniprot Accession | O75150 | | Bait Uniprot Identifier | BRE1B_HUMAN | | Bait Gene Name | RNF40 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 109-113 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20804 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10944455 | | Comments | The Rb-binding LxCxE motif in the Human E3 ubiquitin-protein ligase BRE1B/RBP95/RNF40, a novel leucine zipper protein, that mediates binding to the human retinoblastoma protein (RB) |
Record No : 30 |
| Instance ID | 10805 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LTCHE | | Bait Uniprot Accession | P03255 | | Bait Uniprot Identifier | E1A_ADE05 | | Bait Gene Name | Not Available | | Bait Organism | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) | | Sequence Position | 122-126 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Competition binding | | Interaction ID | 20805 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8084002, 1534854 | | Comments | The Rb-binding LxCxE motif in the Human adenovirus Early E1A 32 kDa protein that mediates binding to the human retinoblastoma protein (RB) |
Record No : 31 |
| Instance ID | 10806 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LFCSE | | Bait Uniprot Accession | P03070 | | Bait Uniprot Identifier | LT_SV40 | | Bait Gene Name | Not Available | | Bait Organism | Simian virus 40 (SV40) | | Sequence Position | 103-107 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis; X-ray crystallography | | Interaction ID | 20806 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 2839300, 11226179 | | Comments | The Rb-binding LxCxE motif in the SV40 large T antigen that mediates binding to the human retinoblastoma protein (RB) |
Record No : 32 |
| Instance ID | 11802 | | Regular Expression | [DE][LI]xCxE | | Motif Instance | DLYCHE | | Bait Uniprot Accession | Q98178 | | Bait Uniprot Identifier | Q98178_MCV1 | | Bait Gene Name | MC007L | | Bait Organism | Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) | | Sequence Position | 140-145 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 21802 | | Interacting Domain | B domain | | Disease Association(s) | Molluscum contagiosum | | Inhibitor(s) | Unknown | | Reference(s) | 18701596 | | Comments | The MC007L protein of Molluscum contagiosum virus (MCV) targets human retinoblastoma protein (RB) via a conserved LxCxE motif (140-145) |
Record No : 33 |
| Instance ID | 12172 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LSCDE | | Bait Uniprot Accession | K7WGV9 | | Bait Uniprot Identifier | K7WGV9_9VIRU | | Bait Gene Name | wssv_00560 | | Bait Organism | White spot syndrome virus | | Sequence Position | 216-220 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP | | Interaction ID | 22172 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24027329 | | Comments | The conserved LxCxE motif in Wsv056 protein of White spot syndrome virus (WSSV), a major pathogen of shrimp, that mediates binding to the Retinoblastoma family-like protein (RBL) of Litopenaeus vannamei (Whiteleg shrimp) |
Record No : 34 |
| Instance ID | 12173 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LSCDE | | Bait Uniprot Accession | K7WGV9 | | Bait Uniprot Identifier | K7WGV9_9VIRU | | Bait Gene Name | wssv_00560 | | Bait Organism | White spot syndrome virus | | Sequence Position | 216-220 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP | | Interaction ID | 22173 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24027329 | | Comments | The conserved LxCxE motif in Wsv056 protein of White spot syndrome virus (WSSV) that mediates binding to the Transcription factor E2f2 of Drosophila melanogaster |
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