Query 'BIR domain' matched 10 Records
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Record No : 1 |
| Instance ID | 10202 | | Regular Expression | ^M{0,1}AxPx | | Motif Instance | MAVPF | | Bait Uniprot Accession | O14757 | | Bait Uniprot Identifier | CHK1_HUMAN | | Bait Gene Name | CHEK1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1-5 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Co-IP | | Interaction ID | 20202 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14759516 | | Comments | IAP-binding motif in human Cell cycle checkpoint kinase CHK1 that mediates the interaction between CHK1 and the BIR3 domain of XIAP |
Record No : 2 |
| Instance ID | 10203 | | Regular Expression | DAxPx | | Motif Instance | DAAPV | | Bait Uniprot Accession | Q7K4Z4 | | Bait Uniprot Identifier | Q7K4Z4_DROME | | Bait Gene Name | imd | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 30-34 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20203 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20122400 | | Comments | IAP-binding motif in Drosophila imd protein that preferentially binds to the BIR2 domain of Drosophila Iap2 (dIAP2) |
Record No : 3 |
| Instance ID | 10204 | | Regular Expression | DAxPx | | Motif Instance | DAKPD | | Bait Uniprot Accession | P55210 | | Bait Uniprot Identifier | CASP7_HUMAN | | Bait Gene Name | CASP7 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 23-27 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20204 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15580265, 19258326 | | Comments | BIR domain-binding motif of human Caspase-7 that mediates binding to the BIR domains of Baculoviral IAP repeat-containing protein 2 |
Record No : 4 |
| Instance ID | 10205 | | Regular Expression | DAxPx | | Motif Instance | DATPF | | Bait Uniprot Accession | P55211 | | Bait Uniprot Identifier | CASP9_HUMAN | | Bait Gene Name | CASP9 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 315-319 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; X-ray crystallography; SPR | | Interaction ID | 20205 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12620238, 19153467 | | Comments | BIR domain-binding motif of human Caspase-9 that mediates binding to the BIR domains of Baculoviral IAP repeat-containing protein 4 (XIAP) |
Record No : 5 |
| Instance ID | 10206 | | Regular Expression | ^M{0,1}Ax[AP]x | | Motif Instance | MAVPF | | Bait Uniprot Accession | Q24106 | | Bait Uniprot Identifier | HID_DROME | | Bait Gene Name | W | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1-5 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20206 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11511363 | | Comments | IAP-binding motif in Drosophila Cell death protein W or Hid that binds to the BIR2 domain of Drosophila Iap2 (dIAP2) |
Record No : 6 |
| Instance ID | 10207 | | Regular Expression | ^M{0,1}Ax[AP]x | | Motif Instance | MAIAY | | Bait Uniprot Accession | Q24570 | | Bait Uniprot Identifier | GRIM_DROME | | Bait Gene Name | grim | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1-5 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20207 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11511363, 15107838 | | Comments | IAP-binding motif in Drosophila Cell death protein Grim that binds to the BIR2 domain of Drosophila Iap2 (dIAP2) |
Record No : 7 |
| Instance ID | 10208 | | Regular Expression | ^M{0,1}Ax[AP]x | | Motif Instance | MAVAF | | Bait Uniprot Accession | Q24475 | | Bait Uniprot Identifier | RPR_DROME | | Bait Gene Name | rpr | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1-5 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography | | Interaction ID | 20208 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15107838 | | Comments | IAP-binding motif in Drosophila Cell death protein rpr that binds to the BIR2 domain of Drosophila Iap2 (dIAP2) |
Record No : 8 |
| Instance ID | 10209 | | Regular Expression | ^M{0,1}Ax[AP]x | | Motif Instance | MAIPF | | Bait Uniprot Accession | Q9VVP8 | | Bait Uniprot Identifier | Q9VVP8_DROME | | Bait Gene Name | skl | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 1-5 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography; Pull down; Mutation analysis | | Interaction ID | 20209 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11818063 | | Comments | IAP-binding motif in Drosophila IAP-inhibitory protein Sickle that binds to the BIR2 domain of Drosophila Iap2 (dIAP2) |
Record No : 9 |
| Instance ID | 10210 | | Regular Expression | DAxGx | | Motif Instance | DALGS | | Bait Uniprot Accession | O01382 | | Bait Uniprot Identifier | ICE_DROME | | Bait Gene Name | Ice | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 28-32 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20210 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15580265 | | Comments | IAP-binding motif in Drosophila effector caspase drICE that binds to the BIR1 domain of Drosophila IAP1 (dIAP1) |
Record No : 10 |
| Instance ID | 10211 | | Regular Expression | DAxGx | | Motif Instance | DAKGC | | Bait Uniprot Accession | O02002 | | Bait Uniprot Identifier | CASP1_DROME | | Bait Gene Name | Dcp-1 | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 33-37 | | Critical Residues | P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20211 | | Interacting Domain | BIR domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15580265 | | Comments | IAP-binding motif in Drosophila effector caspase DCP-1 that binds to the BIR1 domain of Drosophila IAP1 (dIAP1) |
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