Query 'Galactose oxidase, central domain' matched 12 Records
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Record No : 1 |
| Instance ID | 10454 | | Regular Expression | [DE]HxY | | Motif Instance | DHDY | | Bait Uniprot Accession | Q9NS37 | | Bait Uniprot Identifier | ZHANG_HUMAN | | Bait Gene Name | CREBZF | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 303-306 | | Critical Residues | P1; P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down(GST tag); Mammalian two-hybrid assay | | Interaction ID | 20454 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Herpes simplex virus (HSV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 15705566, 10871379 | | Comments | Human HCF-binding transcription factor Zhangfei (CREB/ATF bZIP transcription factor or CREBZF) associates with human Host cell factor 1 through a conserved sequence motif |
Record No : 2 |
| Instance ID | 10455 | | Regular Expression | [DE]HxY | | Motif Instance | DHPY | | Bait Uniprot Accession | Q9NWW0 | | Bait Uniprot Identifier | HPIP_HUMAN | | Bait Gene Name | HCFC1R1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 76-79 | | Critical Residues | P1; P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Y2H; Mutation analysis | | Interaction ID | 20455 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Herpes simplex virus (HSV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 12235138 | | Comments | Interaction of human Host cell factor 1 (HCF-1) with a HCF-1 beta-propeller domain binding protein, termed HPIP, mediated by a HCF-binding motif or HBM in HPIP, through which HPIP regulates HCF-1 activity by modulating its subcellular localization |
Record No : 3 |
| Instance ID | 10456 | | Regular Expression | [DE]HxY | | Motif Instance | DHDY | | Bait Uniprot Accession | Q16254 | | Bait Uniprot Identifier | E2F4_HUMAN | | Bait Gene Name | E2F4 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 389-392 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 20456 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16633736 | | Comments | Transcription factor E2F4 specifically and directly interacts with human Host Cell Factor (HCF-1) via a consensus HCF-binding motif (HBM) present in E2F4, suggesting a linkage between E2F4 and HCF-1 cell growth pathways |
Record No : 4 |
| Instance ID | 10457 | | Regular Expression | [DE]HxY | | Motif Instance | EHSY | | Bait Uniprot Accession | P29747 | | Bait Uniprot Identifier | CREBA_DROME | | Bait Gene Name | CrebA | | Bait Organism | Drosophila melanogaster (Fruit fly) | | Sequence Position | 64-67 | | Critical Residues | P1; P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 20457 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9658067, 9389645 | | Comments | The Drosophila protein dCREB-A contains an HCF-binding motif that has been implicated in its association with human Host Cell Factor (HCF-1) |
Record No : 5 |
| Instance ID | 10458 | | Regular Expression | [DE]HxY | | Motif Instance | DHSY | | Bait Uniprot Accession | Q9JJD0 | | Bait Uniprot Identifier | THA11_MOUSE | | Bait Gene Name | Thap11 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 234-237 | | Critical Residues | P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20458 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20581084 | | Comments | The zinc finger transcriptional regulator, Ronin (Thap11), can interact with the cell growth factor Hcf-1, via a consensus HCF-binding motif (HBM), and together Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of mouse embryonic stem cells |
Record No : 6 |
| Instance ID | 10459 | | Regular Expression | [DE]HxY | | Motif Instance | DHNY | | Bait Uniprot Accession | Q9NVV9 | | Bait Uniprot Identifier | THAP1_HUMAN | | Bait Gene Name | THAP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 134-137 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Y2H | | Interaction ID | 20459 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Neurological disease | | Inhibitor(s) | Unknown | | Reference(s) | 20200153 | | Comments | The Human THAP-zinc finger protein THAP1 associates with coactivator HCF-1 through its HCF-1-binding motif (HBM) |
Record No : 7 |
| Instance ID | 10460 | | Regular Expression | [DE]HxY | | Motif Instance | DHDY | | Bait Uniprot Accession | Q5VV67 | | Bait Uniprot Identifier | PPRC1_HUMAN | | Bait Gene Name | PPRC1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1295-1298 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis | | Interaction ID | 20460 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18343819 | | Comments | Human PGC-1-related coactivator complexes with HCF-1 through its HCF-1 binding site |
Record No : 8 |
| Instance ID | 10461 | | Regular Expression | [DE]HxY | | Motif Instance | DHLY | | Bait Uniprot Accession | P08152 | | Bait Uniprot Identifier | EGR2_MOUSE | | Bait Gene Name | Egr2 | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 162-165 | | Critical Residues | P1; P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20461 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14532282 | | Comments | The HCF-binding motif in murine Zinc finger protein Krox-20 (Egr2) that binds to a six-bladed beta-propeller domain at the N terminus of HCF-1 |
Record No : 9 |
| Instance ID | 10462 | | Regular Expression | [DE]HxY | | Motif Instance | DHSY | | Bait Uniprot Accession | Q8WTV1 | | Bait Uniprot Identifier | THAP3_HUMAN | | Bait Gene Name | THAP3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 177-180 | | Critical Residues | P1; P2; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; AP-MS; Pull down(GST tag) | | Interaction ID | 20462 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20200153 | | Comments | The Human THAP-zinc finger protein THAP3 associates with coactivator HCF-1 through its HCF-1-binding motif (HBM) |
Record No : 10 |
| Instance ID | 10463 | | Regular Expression | [DE]HxY | | Motif Instance | EHAY | | Bait Uniprot Accession | P06492 | | Bait Uniprot Identifier | VP16_HHV11 | | Bait Gene Name | ORF_Name:UL48 | | Bait Organism | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) | | Sequence Position | 361-364 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20463 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Herpes simplex virus (HSV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 9389645 | | Comments | The herpes simplex virus protein VP16 associates with the endogenous cell-proliferation factor HCF-1 through its HCF-1-binding motif (HBM) |
Record No : 11 |
| Instance ID | 10464 | | Regular Expression | [DE]HxY | | Motif Instance | DHQY | | Bait Uniprot Accession | Q01094 | | Bait Uniprot Identifier | E2F1_HUMAN | | Bait Gene Name | E2F1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 97-100 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis; Y2H | | Interaction ID | 20464 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16633736, 17612494 | | Comments | The human G1 phase regulator HCF-1 displays coactivator properties when bound to the E2F1 transcriptional activator, but full-length E2F1 has regions that can inhibit its own interaction with the HCF-1 Kelch domain, suggesting that E2F1 has a latent ability to associate with HCF-1 |
Record No : 12 |
| Instance ID | 10465 | | Regular Expression | [DE]HxY | | Motif Instance | DHTY | | Bait Uniprot Accession | O43889 | | Bait Uniprot Identifier | CREB3_HUMAN | | Bait Gene Name | CREB3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 78-81 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down(GST tag); Mammalian two-hybrid assay; Mutation analysis | | Interaction ID | 20465 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9658067, 9389645 | | Comments | The human basic domain leucine zipper protein, Luman (CREB3/LZIP), interacts with the cellular transcription factor HCF-1 through its HCF-1-binding motif (HBM) |
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