Query 'MYND domain' matched 13 Records
|
Record No : 1 |
| Instance ID | 10541 | | Regular Expression | PxLxP | | Motif Instance | PNLVP | | Bait Uniprot Accession | P03255 | | Bait Uniprot Identifier | E1A_ADE05 | | Bait Gene Name | Not Available | | Bait Organism | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) | | Sequence Position | 113-117 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation disrupting interaction; Mutation analysis; Co-IP; Pull down(GST tag) | | Interaction ID | 20541 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11733528 | | Comments | The conserved Mynd domain of human protein BS69 (ZMYND11) binds the adenoviral E1A oncoprotein through a PxLxP motif |
Record No : 2 |
| Instance ID | 10542 | | Regular Expression | PxLxP | | Motif Instance | PELSP | | Bait Uniprot Accession | P12978 | | Bait Uniprot Identifier | EBNA2_EBVB9 | | Bait Gene Name | EBNA2 | | Bait Organism | Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) | | Sequence Position | 383-387 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Mutation disrupting interaction; Mutation analysis; Co-IP; Y2H | | Interaction ID | 20542 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11733528 | | Comments | The conserved Mynd domain of human protein BS69 (ZMYND11) binds the Epstein-Barr virus EBNA2 oncoprotein through a PxLxP motif (383-387) |
Record No : 3 |
| Instance ID | 10543 | | Regular Expression | PxLxP | | Motif Instance | PILFP | | Bait Uniprot Accession | P12978 | | Bait Uniprot Identifier | EBNA2_EBVB9 | | Bait Gene Name | EBNA2 | | Bait Organism | Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) | | Sequence Position | 437-441 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Mutation disrupting interaction; Mutation analysis; Co-IP; Y2H | | Interaction ID | 20543 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 11733528 | | Comments | The conserved Mynd domain of human protein BS69 (ZMYND11) binds the Epstein-Barr virus EBNA2 oncoprotein through a PxLxP motif (437-441) |
Record No : 4 |
| Instance ID | 10544 | | Regular Expression | PxLxP | | Motif Instance | PKLAP | | Bait Uniprot Accession | Q8IWI9 | | Bait Uniprot Identifier | MGAP_HUMAN | | Bait Gene Name | MGA | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 2948-2952 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Mutation disrupting interaction; Mutation analysis; Y2H | | Interaction ID | 20544 | | Interacting Domain | MYND domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11733528 | | Comments | The conserved Mynd domain of human protein BS69 (ZMYND11) binds the the Myc-related cellular protein MGA through a PxLxP motif (2948-2952) |
Record No : 5 |
| Instance ID | 10545 | | Regular Expression | PxLxP | | Motif Instance | PCLAP | | Bait Uniprot Accession | Q8IWI9 | | Bait Uniprot Identifier | MGAP_HUMAN | | Bait Gene Name | MGA | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 2973-2977 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Mutation disrupting interaction; Mutation analysis; Y2H | | Interaction ID | 20545 | | Interacting Domain | MYND domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11733528 | | Comments | The conserved Mynd domain of human protein BS69 (ZMYND11) binds the the Myc-related cellular protein MGA through a PxLxP motif (2973-2977) |
Record No : 6 |
| Instance ID | 10546 | | Regular Expression | PxLxP | | Motif Instance | PPLIP | | Bait Uniprot Accession | P70670 | | Bait Uniprot Identifier | NACAM_MOUSE | | Bait Gene Name | Naca | | Bait Organism | Mus musculus (Mouse) | | Sequence Position | 1950-1954 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Colocalization; Mutation disrupting interaction; Mutation analysis; Co-IP | | Interaction ID | 20546 | | Interacting Domain | MYND domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12011100 | | Comments | The PxLxP motif in mouse skNAC (Naca) that is required for interaction with mouse Zinc finger protein BOP (Smyd1) |
Record No : 7 |
| Instance ID | 10547 | | Regular Expression | PPxLI | | Motif Instance | PPYLI | | Bait Uniprot Accession | Q9Y618 | | Bait Uniprot Identifier | NCOR2_HUMAN | | Bait Gene Name | NCOR2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1674-1678 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | ITC; Fluorescence polarization spectroscopy | | Interaction ID | 20547 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 17560331 | | Comments | SMRT(NCOR2) recruitment by the MYND domain of AML1/ETO through the PPxLI motif (1674-1678) of SMRT plays a key role in AML1/ETO's ability to repress proliferation and differentiation of primary bone marrow cells as well as to enhance their self renewal |
Record No : 8 |
| Instance ID | 10548 | | Regular Expression | PPxLI | | Motif Instance | PPPLI | | Bait Uniprot Accession | O75376 | | Bait Uniprot Identifier | NCOR1_HUMAN | | Bait Gene Name | NCOR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1033-1037 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; ITC; Fluorescence polarization spectroscopy | | Interaction ID | 20548 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 23372760, 17560331 | | Comments | N-CoR (NCOR1) recruitment by the MYND domain of AML1/ETO through the PPxLI motif (1033-1037) of N-CoR plays a key role in AML1/ETO's ability to repress proliferation and differentiation of primary bone marrow cells as well as to enhance their self renewal |
Record No : 9 |
| Instance ID | 10549 | | Regular Expression | PPxLI | | Motif Instance | PPPLI | | Bait Uniprot Accession | O75376 | | Bait Uniprot Identifier | NCOR1_HUMAN | | Bait Gene Name | NCOR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1033-1037 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; ITC; Fluorescence polarization spectroscopy | | Interaction ID | 20549 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 23372760, 17560331 | | Comments | Human DEAF-1 transcription regulation activity is mediated through its interaction with Nuclear receptor corepressor 1 (NCOR1) via its MYND domain that binds to the PPxLI motif (1033-1037) of N-CoR |
Record No : 10 |
| Instance ID | 10550 | | Regular Expression | PPxLI | | Motif Instance | PPPLI | | Bait Uniprot Accession | Q9Y618 | | Bait Uniprot Identifier | NCOR2_HUMAN | | Bait Gene Name | NCOR2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1113-1117 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; ITC; Fluorescence polarization spectroscopy | | Interaction ID | 20550 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 23372760, 17560331 | | Comments | SMRT(NCOR2) recruitment by the MYND domain of AML1/ETO through the PPxLI motif (1113-1117) of SMRT plays a key role in AML1/ETO's ability to repress proliferation and differentiation of primary bone marrow cells as well as to enhance their self renewal |
Record No : 11 |
| Instance ID | 10551 | | Regular Expression | PPxLI | | Motif Instance | PPPLI | | Bait Uniprot Accession | Q9Y618 | | Bait Uniprot Identifier | NCOR2_HUMAN | | Bait Gene Name | NCOR2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1113-1117 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; ITC; Fluorescence polarization spectroscopy | | Interaction ID | 20551 | | Interacting Domain | MYND domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 23372760, 17560331 | | Comments | Human DEAF-1 transcription regulation activity is mediated through its interaction with Nuclear receptor corepressor 2 (NCOR2/SMRT) via its MYND domain that binds to the PPxLI motif (1113-1117) of SMRT |
Record No : 12 |
| Instance ID | 10552 | | Regular Expression | [LMV]PxLE | | Motif Instance | MPDLE | | Bait Uniprot Accession | Q15185 | | Bait Uniprot Identifier | TEBP_HUMAN | | Bait Gene Name | PTGES3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 156-160 | | Critical Residues | P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning; Mutation analysis; Western blot; RNA interference; Co-IP; Mass spectrometry; Co-IP | | Interaction ID | 20552 | | Interacting Domain | MYND domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 23413029 | | Comments | The MYND-type Zinc Finger of human Prolyl hydroxylase domain protein 2 (PHD2/EGLN1) binds a PxLE motif found in human HSP90 co-chaperone p23 (PTGES3) |
Record No : 13 |
| Instance ID | 10553 | | Regular Expression | [LMV]PxLE | | Motif Instance | LPPLE | | Bait Uniprot Accession | Q14318 | | Bait Uniprot Identifier | FKBP8_HUMAN | | Bait Gene Name | FKBP8 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 52-56 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | FRET; subcellular preparation; Colocalization; Pull down; Mutation analysis; ITC; Fluorescence polarization spectroscopy; Competition binding; Affinity chromatography technology; protein array; Co-IP; Mass spectrometry | | Interaction ID | 20553 | | Interacting Domain | MYND domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19546213, 23413029 | | Comments | The MYND-type Zinc Finger of human Prolyl hydroxylase domain protein 2 (PHD2/EGLN1) binds a PxLE motif found in human Peptidyl-prolyl cis-trans isomerase FKBP8 (or FKBP38) |
|
