Query 'UEV domain' matched 18 Records
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Record No : 1 |
| Instance ID | 10717 | | Regular Expression | xP[TS]APx | | Motif Instance | VPTAPA | | Bait Uniprot Accession | O75674 | | Bait Uniprot Identifier | TM1L1_HUMAN | | Bait Gene Name | TOM1L1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 178-183 | | Critical Residues | P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Alanine scanning; Pull down | | Interaction ID | 20717 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18367816 | | Comments | The UEV Domain binding P[TS]AP motif (178-183) in human TOM1L1 that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 2 |
| Instance ID | 10718 | | Regular Expression | xP[TS]APx | | Motif Instance | LPTAPP | | Bait Uniprot Accession | Q05128 | | Bait Uniprot Identifier | VP40_EBOZM | | Bait Gene Name | VP40 | | Bait Organism | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus) | | Sequence Position | 6-11 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20718 | | Interacting Domain | UEV domain | | Disease Association(s) | Ebola virus infection | | Inhibitor(s) | Unknown | | Reference(s) | 12525615 | | Comments | The UEV Domain binding P[TS]AP motif in Membrane-associated Matrix protein VP40 of Zaire Ebola virus that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 3 |
| Instance ID | 10719 | | Regular Expression | xP[TS]APx | | Motif Instance | EPTAPP | | Bait Uniprot Accession | P04591 | | Bait Uniprot Identifier | GAG_HV1H2 | | Bait Gene Name | gag | | Bait Organism | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) | | Sequence Position | 454-459 | | Critical Residues | P2; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | NMR; Electron microscopy; Alanine scanning; SPR; Mutation analysis; Co-IP; Y2H; Competition binding | | Interaction ID | 20719 | | Interacting Domain | UEV domain | | Disease Association(s) | Human immunodeficiency virus (HIV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 12379843, 11595185, 11427703, 11805336 | | Comments | The UEV Domain binding P[TS]AP motif in Gag polyprotein of Human immunodeficiency virus type 1 group M subtype B that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 4 |
| Instance ID | 10720 | | Regular Expression | xP[TS]APx | | Motif Instance | TPTAPQ | | Bait Uniprot Accession | Q6UWE0 | | Bait Uniprot Identifier | LRSM1_HUMAN | | Bait Gene Name | LRSAM1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 648-653 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20720 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15256501 | | Comments | Bivalent binding of the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) to the PTAP motif (648-653) of human TAL (TSG101-associated ligase), also known as E3 ubiquitin-protein ligase LRSAM1, is essential for TAL-mediated ubiquitylation of TSG101 |
Record No : 5 |
| Instance ID | 10721 | | Regular Expression | xP[TS]APx | | Motif Instance | RPSAPP | | Bait Uniprot Accession | Q6UWE0 | | Bait Uniprot Identifier | LRSM1_HUMAN | | Bait Gene Name | LRSAM1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 660-665 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20721 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15256501 | | Comments | Bivalent binding of the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) to the PTAP motif (660-665) of human TAL (TSG101-associated ligase), also known as E3 ubiquitin-protein ligase LRSAM1, is essential for TAL-mediated ubiquitylation of TSG101 |
Record No : 6 |
| Instance ID | 10722 | | Regular Expression | xP[TS]APx | | Motif Instance | IPSAPL | | Bait Uniprot Accession | O60291 | | Bait Uniprot Identifier | MGRN1_HUMAN | | Bait Gene Name | MGRN1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 405-410 | | Critical Residues | P2; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Pull down; Co-IP; Classical fluorescence spectroscopy; Y2H | | Interaction ID | 20722 | | Interacting Domain | UEV domain | | Disease Association(s) | Spongiform Neurodegeneration | | Inhibitor(s) | Unknown | | Reference(s) | 17229889 | | Comments | Spongiform neurodegeneration-associated E3 ubiquitin-protein ligase Mahogunin (MGRN1) ubiquitylates human Tumor susceptibility gene 101 protein (TSG101) and thereby regulates endosomal trafficking |
Record No : 7 |
| Instance ID | 10723 | | Regular Expression | xP[TS]APx | | Motif Instance | EPSAPS | | Bait Uniprot Accession | Q8WUM4 | | Bait Uniprot Identifier | PDC6I_HUMAN | | Bait Gene Name | PDCD6IP | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 716-721 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Co-IP; Mutation analysis | | Interaction ID | 20723 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17853893 | | Comments | The UEV Domain binding P[TS]AP motif in Human PDCD6-interacting protein (PDCD6IP)/AIP1/ALIX that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 8 |
| Instance ID | 10724 | | Regular Expression | xP[TS]APx | | Motif Instance | APTAPL | | Bait Uniprot Accession | Q9H9H4 | | Bait Uniprot Identifier | VP37B_HUMAN | | Bait Gene Name | VPS37B | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 184-189 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20724 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15218037 | | Comments | The UEV Domain binding P[TS]AP motif in Human ESCRT-I complex subunit VPS37B that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 9 |
| Instance ID | 10725 | | Regular Expression | xP[TS]APx | | Motif Instance | IPTAPL | | Bait Uniprot Accession | Q99816 | | Bait Uniprot Identifier | TS101_HUMAN | | Bait Gene Name | TSG101 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 319-324 | | Critical Residues | P2; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Y2H | | Interaction ID | 20725 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12802020 | | Comments | The UEV Domain binding P[TS]AP motif in Human ESCRT-I complex subunit TSG101 that can bind to its own UEV domain through intermolecular or intramolecular interaction |
Record No : 10 |
| Instance ID | 10726 | | Regular Expression | xP[TS]APx | | Motif Instance | TPSAPT | | Bait Uniprot Accession | P07567 | | Bait Uniprot Identifier | GAG_MPMV | | Bait Gene Name | gag | | Bait Organism | Mason-Pfizer monkey virus (MPMV) (Simian Mason-Pfizer virus) | | Sequence Position | 209-214 | | Critical Residues | P2; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Electron microscopy; Mutation analysis | | Interaction ID | 20726 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12915562 | | Comments | The UEV Domain binding P[TS]AP motif in Gag polyprotein of Mason-Pfizer monkey virus (MPMV) that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 11 |
| Instance ID | 10727 | | Regular Expression | xP[TS]APx | | Motif Instance | EPSAPS | | Bait Uniprot Accession | O75674 | | Bait Uniprot Identifier | TM1L1_HUMAN | | Bait Gene Name | TOM1L1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 309-314 | | Critical Residues | P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Alanine scanning | | Interaction ID | 20727 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18367816 | | Comments | The UEV Domain binding P[TS]AP motif (309-314) in human TOM1L1 that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 12 |
| Instance ID | 10728 | | Regular Expression | xP[TS]APx | | Motif Instance | PPSAPS | | Bait Uniprot Accession | O14828 | | Bait Uniprot Identifier | SCAM3_HUMAN | | Bait Gene Name | SCAMP3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 63-68 | | Critical Residues | P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | SPR; Mutation analysis | | Interaction ID | 20728 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 19158374 | | Comments | Human Secretory carrier-associated membrane protein SCAMP3 localizes in part to early endosomes and negatively regulates EGFR degradation through processes that involve its ubiquitylation and interactions with the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 13 |
| Instance ID | 10729 | | Regular Expression | xP[TS]APx | | Motif Instance | EPTAPQ | | Bait Uniprot Accession | P03345 | | Bait Uniprot Identifier | GAG_HTL1A | | Bait Gene Name | gag | | Bait Organism | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | | Sequence Position | 123-128 | | Critical Residues | P2; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Y2H; Alanine scanning; Mutation analysis; Pull down | | Interaction ID | 20729 | | Interacting Domain | UEV domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 14581525 | | Comments | The UEV Domain binding P[TS]AP motif in Gag polyprotein of human T-cell leukemia virus type 1 (HTLV-1) that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 14 |
| Instance ID | 10730 | | Regular Expression | xP[TS]APx | | Motif Instance | VPSAPP | | Bait Uniprot Accession | P14349 | | Bait Uniprot Identifier | GAG_FOAMV | | Bait Gene Name | gag | | Bait Organism | Human spumaretrovirus (SFVcpz(hu)) (Human foamy virus) | | Sequence Position | 283-288 | | Critical Residues | P2; P3; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20730 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15858022 | | Comments | The UEV Domain binding P[TS]AP motif in Gag polyprotein of Human foamy virus that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) |
Record No : 15 |
| Instance ID | 10731 | | Regular Expression | xP[TS]APx | | Motif Instance | APSAPM | | Bait Uniprot Accession | P08363 | | Bait Uniprot Identifier | VP8_BTV10 | | Bait Gene Name | S10 | | Bait Organism | Bluetongue virus 10 (isolate USA) (BTV 10) | | Sequence Position | 40-45 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Confocal microscopy; Pull down; Mutation analysis | | Interaction ID | 20731 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16352570 | | Comments | The UEV Domain binding P[TS]AP motif in Non-structural protein NS3 of Bluetongue virus 10 that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 16 |
| Instance ID | 10732 | | Regular Expression | xP[TS]APx | | Motif Instance | SPSAPQ | | Bait Uniprot Accession | P27588 | | Bait Uniprot Identifier | NCAP_MABVM | | Bait Gene Name | NP | | Bait Organism | Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980)) | | Sequence Position | 602-607 | | Critical Residues | P2; P3; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Co-IP; Mutation analysis | | Interaction ID | 20732 | | Interacting Domain | UEV domain | | Disease Association(s) | Marburg virus infection | | Inhibitor(s) | Unknown | | Reference(s) | 20504928 | | Comments | The UEV Domain binding P[TS]AP motif in Nucleocapsid protein of Marburg virus that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 17 |
| Instance ID | 10733 | | Regular Expression | xP[TS]APx | | Motif Instance | RPSAPP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Bait Organism | Hepatitis E virus genotype 1 (isolate Human/Burma) (HEV-1) | | Sequence Position | 95-100 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Co-IP; Mutation analysis | | Interaction ID | 20733 | | Interacting Domain | UEV domain | | Disease Association(s) | Hepatitis E | | Inhibitor(s) | Unknown | | Reference(s) | 21068219 | | Comments | The UEV Domain binding P[TS]AP motif in Protein ORF3 of Hepatitis E virus genotype 1 that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 18 |
| Instance ID | 10734 | | Regular Expression | xP[TS]APx | | Motif Instance | TPSAPV | | Bait Uniprot Accession | O14964 | | Bait Uniprot Identifier | HGS_HUMAN | | Bait Gene Name | HGS | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 347-352 | | Critical Residues | P2; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | X-ray crystallography; Mutation analysis | | Interaction ID | 20734 | | Interacting Domain | UEV domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21070952, 12802020 | | Comments | The UEV Domain binding P[TS]AP motif in Human Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS) that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
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