Query 'WH1 domain' matched 33 Records
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Record No : 1 |
| Instance ID | 10421 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | WPPPP | | Bait Uniprot Accession | P51617 | | Bait Uniprot Identifier | IRAK1_HUMAN | | Bait Gene Name | IRAK1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 168-172 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Co-IP; Western blot | | Interaction ID | 20421 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20044140 | | Comments | Proline-rich motif within human Interleukin-1 receptor-associated kinase 1 (IRAK-1) that is required for its interaction with VASP |
Record No : 2 |
| Instance ID | 10422 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | O15117 | | Bait Uniprot Identifier | FYB_HUMAN | | Bait Gene Name | FYB | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 616-620 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Ligand overlay assay; Co-IP; Far Western blotting | | Interaction ID | 20422 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10747096 | | Comments | Proline-rich motif within human FYN-binding protein (FYB/SLAP130) that is required for its interaction with VASP |
Record No : 3 |
| Instance ID | 10423 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | Q15942 | | Bait Uniprot Identifier | ZYX_HUMAN | | Bait Gene Name | ZYX | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 93-97 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20423 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10801818 | | Comments | Proline-rich motif (93-97) within human Zyxin that is required for its interaction with ENAH |
Record No : 4 |
| Instance ID | 10424 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPSPP | | Bait Uniprot Accession | Q15942 | | Bait Uniprot Identifier | ZYX_HUMAN | | Bait Gene Name | ZYX | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 114-118 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20424 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10801818 | | Comments | Proline-rich motif (114-118) within human Zyxin that is required for its interaction with ENAH |
Record No : 5 |
| Instance ID | 10425 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPAP | | Bait Uniprot Accession | Q15942 | | Bait Uniprot Identifier | ZYX_HUMAN | | Bait Gene Name | ZYX | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 104-108 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20425 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10801818 | | Comments | Proline-rich motif (104-108) within human Zyxin that is required for its interaction with ENAH |
Record No : 6 |
| Instance ID | 10426 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPSPP | | Bait Uniprot Accession | Q04584 | | Bait Uniprot Identifier | ZYX_CHICK | | Bait Gene Name | ZYX | | Bait Organism | Gallus gallus (Chicken) | | Sequence Position | 121-125 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down(GST tag) | | Interaction ID | 20426 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9693373 | | Comments | Proline-rich motif (121-125) within chicken zyxin that is required for its interaction with ENAH |
Record No : 7 |
| Instance ID | 10427 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPAP | | Bait Uniprot Accession | Q04584 | | Bait Uniprot Identifier | ZYX_CHICK | | Bait Gene Name | ZYX | | Bait Organism | Gallus gallus (Chicken) | | Sequence Position | 113-117 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down(GST tag) | | Interaction ID | 20427 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9693373 | | Comments | Proline-rich motif (113-117) within chicken zyxin that is required for its interaction with ENAH |
Record No : 8 |
| Instance ID | 10428 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | Q04584 | | Bait Uniprot Identifier | ZYX_CHICK | | Bait Gene Name | ZYX | | Bait Organism | Gallus gallus (Chicken) | | Sequence Position | 102-106 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down(GST tag) | | Interaction ID | 20428 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9693373 | | Comments | Proline-rich motif (102-106) within chicken zyxin that is required for its interaction with ENAH |
Record No : 9 |
| Instance ID | 10429 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | P12003 | | Bait Uniprot Identifier | VINC_CHICK | | Bait Gene Name | VCL | | Bait Organism | Gallus gallus (Chicken) | | Sequence Position | 842-846 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting | | Interaction ID | 20429 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 8980130 | | Comments | Proline-rich motif within chicken Vinculin that is required for its interaction with VASP |
Record No : 10 |
| Instance ID | 10430 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 380-384 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay; Blot overlay assay | | Interaction ID | 20430 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (380-384) present in ActA of Listeria monocytogenes that is required for its interaction with VASP |
Record No : 11 |
| Instance ID | 10431 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 380-384 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay | | Interaction ID | 20431 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (380-384) present in ActA of Listeria monocytogenes that is required for its interaction with ENAH |
Record No : 12 |
| Instance ID | 10432 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | Q12955 | | Bait Uniprot Identifier | ANK3_HUMAN | | Bait Gene Name | ANK3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 3254-3258 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding to perpetrator | | Interaction ID | 20432 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif present in human Ankyrin-G that is required for its interaction with VASP |
Record No : 13 |
| Instance ID | 10433 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPPP | | Bait Uniprot Accession | Q12955 | | Bait Uniprot Identifier | ANK3_HUMAN | | Bait Gene Name | ANK3 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 3254-3258 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding to perpetrator | | Interaction ID | 20433 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif present in human Ankyrin-G that is required for its interaction with ENAH |
Record No : 14 |
| Instance ID | 10434 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 335-339 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay; Blot overlay assay | | Interaction ID | 20434 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (335-339) present in ActA of Listeria monocytogenes that is required for its interaction with VASP |
Record No : 15 |
| Instance ID | 10435 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 335-339 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay | | Interaction ID | 20435 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (335-339) present in ActA of Listeria monocytogenes that is required for its interaction with ENAH |
Record No : 16 |
| Instance ID | 10436 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 265-269 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay; Blot overlay assay | | Interaction ID | 20436 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (265-269) present in ActA of Listeria monocytogenes that is required for its interaction with VASP |
Record No : 17 |
| Instance ID | 10437 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 265-269 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay | | Interaction ID | 20437 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (265-269) present in ActA of Listeria monocytogenes that is required for its interaction with ENAH |
Record No : 18 |
| Instance ID | 10438 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 300-304 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay; Blot overlay assay | | Interaction ID | 20438 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (300-304) present in ActA of Listeria monocytogenes that is required for its interaction with VASP |
Record No : 19 |
| Instance ID | 10439 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPPIP | | Bait Uniprot Accession | P33379 | | Bait Uniprot Identifier | ACTA_LISMO | | Bait Gene Name | actA | | Bait Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) | | Sequence Position | 300-304 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Solid phase binding assay | | Interaction ID | 20439 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9312002 | | Comments | Proline-rich motif (300-304) present in ActA of Listeria monocytogenes that is required for its interaction with ENAH |
Record No : 20 |
| Instance ID | 10440 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | FPLPP | | Bait Uniprot Accession | Q15942 | | Bait Uniprot Identifier | ZYX_HUMAN | | Bait Gene Name | ZYX | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 71-75 | | Critical Residues | P1 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20440 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10801818 | | Comments | Proline-rich motif (71-75) within human Zyxin that is required for its interaction with ENAH |
Record No : 21 |
| Instance ID | 10441 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | LPLPP | | Bait Uniprot Accession | Q702N8 | | Bait Uniprot Identifier | XIRP1_HUMAN | | Bait Gene Name | XIRP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 22-26 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Dot blot; Y2H | | Interaction ID | 20441 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16631741 | | Comments | Proline-rich motif present in human Xin, the protein encoded by the human gene ‘cardiomyopathy associated 1’ (CMYA1), that is required for its interaction with VASP |
Record No : 22 |
| Instance ID | 10442 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | LPLPP | | Bait Uniprot Accession | Q702N8 | | Bait Uniprot Identifier | XIRP1_HUMAN | | Bait Gene Name | XIRP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 22-26 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20442 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16631741 | | Comments | Proline-rich motif present in human Xin, the protein encoded by the human gene ‘cardiomyopathy associated 1’ (CMYA1), that is required for its interaction with ENAH |
Record No : 23 |
| Instance ID | 10443 | | Regular Expression | ([FYWL]PxPP)|([FYWL]PP[ALIVTFY]P) | | Motif Instance | LPLPP | | Bait Uniprot Accession | Q702N8 | | Bait Uniprot Identifier | XIRP1_HUMAN | | Bait Gene Name | XIRP1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 22-26 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20443 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16631741 | | Comments | Proline-rich motif present in human Xin, the protein encoded by the human gene ‘cardiomyopathy associated 1’ (CMYA1), that is required for its interaction with EVL |
Record No : 24 |
| Instance ID | 10444 | | Regular Expression | PPxxF | | Motif Instance | PPVPF | | Bait Uniprot Accession | Q08877 | | Bait Uniprot Identifier | DYN3_RAT | | Bait Gene Name | Dnm3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 809-813 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot | | Interaction ID | 20444 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9808459 | | Comments | Proline-rich motif in rat Dynamin-3 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 25 |
| Instance ID | 10445 | | Regular Expression | PPxxF | | Motif Instance | PPKKF | | Bait Uniprot Accession | Q14643 | | Bait Uniprot Identifier | ITPR1_HUMAN | | Bait Gene Name | ITPR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 49-53 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot | | Interaction ID | 20445 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9808459 | | Comments | Proline-rich motif in human IP3 receptor isoform 1 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 26 |
| Instance ID | 10446 | | Regular Expression | PPxxF | | Motif Instance | PPSPF | | Bait Uniprot Accession | P23385 | | Bait Uniprot Identifier | GRM1_RAT | | Bait Gene Name | Grm1 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1152-1156 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; X-ray crystallography; Western blot; Pull down(GST tag) | | Interaction ID | 20446 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9808459, 10798399 | | Comments | Proline-rich motif in rat Metabotropic glutamate receptor 1 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 27 |
| Instance ID | 10447 | | Regular Expression | PPxxF | | Motif Instance | PPSPF | | Bait Uniprot Accession | P31424 | | Bait Uniprot Identifier | GRM5_RAT | | Bait Gene Name | Grm5 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1156-1160 | | Critical Residues | P1; P2 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down; Mutation analysis | | Interaction ID | 20447 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9808459, 11491285 | | Comments | Proline-rich motif in rat Metabotropic glutamate receptor 5 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 28 |
| Instance ID | 10448 | | Regular Expression | PPxxF | | Motif Instance | PPHHF | | Bait Uniprot Accession | P21817 | | Bait Uniprot Identifier | RYR1_HUMAN | | Bait Gene Name | RYR1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 1773-1777 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down; Co-IP | | Interaction ID | 20448 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12223488 | | Comments | Proline-rich motif in human Ryanodine receptor 1 that is recognized by Class II EVH1 domain of Homer1 by which Homer directly modulates the function of its target protein RyR1 and excitation-contraction coupling in skeletal myotubes |
Record No : 29 |
| Instance ID | 10449 | | Regular Expression | PPxxF | | Motif Instance | PPEEF | | Bait Uniprot Accession | Q9JLU4 | | Bait Uniprot Identifier | SHAN3_RAT | | Bait Gene Name | Shank3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 1385-1389 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down; Co-IP | | Interaction ID | 20449 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10433269 | | Comments | Proline-rich motif (1385-1389) in rat Shank3 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 30 |
| Instance ID | 10450 | | Regular Expression | PPxxF | | Motif Instance | PPPTF | | Bait Uniprot Accession | Q9JLU4 | | Bait Uniprot Identifier | SHAN3_RAT | | Bait Gene Name | Shank3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 908-912 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Pull down; Co-IP | | Interaction ID | 20450 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10433269 | | Comments | Proline-rich motif (908-912) in rat Shank3 that is recognized by Class II EVH1 domain of Homer1 |
Record No : 31 |
| Instance ID | 10451 | | Regular Expression | [FY]x[FW]xxxxx[LMVIF]PxP[DE] | | Motif Instance | YSFHPVEDFPAPE | | Bait Uniprot Accession | Q8TF74 | | Bait Uniprot Identifier | WIPF2_HUMAN | | Bait Gene Name | WIPF2 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 400-412 | | Critical Residues | P1; P3; P8; P9 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis; Alanine scanning | | Interaction ID | 20451 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15265696, 12213210 | | Comments | The EVH1 class III motif found in the human verprolin homologue WIRE (WIPF2) that participates in binding to human Wiskott-Aldrich syndrome protein (WASP) |
Record No : 32 |
| Instance ID | 10452 | | Regular Expression | [FY]x[FW]xxxxx[LMVIF]PxP[DE] | | Motif Instance | FTFHSMEDFPPPD | | Bait Uniprot Accession | Q9Z0G8 | | Bait Uniprot Identifier | WIPF3_RAT | | Bait Gene Name | Wipf3 | | Bait Organism | Rattus norvegicus (Rat) | | Sequence Position | 425-437 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Classical fluorescence spectroscopy; AP-MS; Pull down | | Interaction ID | 20452 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11553796 | | Comments | The EVH1 class III motif found in the rat Corticosteroids and regional expression protein 16 (Cr16 or Wipf3) that participates in binding to bovine Neuronal Wiskott-Aldrich syndrome protein (N-WASP) |
Record No : 33 |
| Instance ID | 10453 | | Regular Expression | [FY]x[FW]xxxxx[LMVIF]PxP[DE] | | Motif Instance | FYFHPISDLPPPE | | Bait Uniprot Accession | O43516 | | Bait Uniprot Identifier | WIPF1_HUMAN | | Bait Gene Name | WIPF1 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 454-466 | | Critical Residues | P1; P3; P8; P9; P12 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; NMR; Mutation analysis; structure based prediction; Alanine scanning; GFP tag; Pull down | | Interaction ID | 20453 | | Interacting Domain | WH1 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12437929, 17229736, 12372256 | | Comments | The rat N-WASP EVH1 domain specifically binds an EVH1 class III motif from the human WASP Interacting Protein (WIP or WIPF1) |
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