|
| Instance ID | 10085 |
| Regular Expression | [IL]xx[^P][^P][^P][^P]Rxxxxx[IL]xx[^P][^P][ILV][ILM] |
| Motif Instance | LKRKIRSRPERAELVRMHIL |
| Bait Uniprot Accession | Q8K4J6 |
| Bait Uniprot Identifier | MKL1_MOUSE |
| Bait Gene Name | Mkl1 |
| Bait Organism | Mus musculus (Mouse) |
| Sequence Position | 61-80 |
| Critical Residues | Unknown |
| Motif PTM(s) | Unknown |
| Secondary Structure | Disordered |
| Experimental Method(s) | Mutation analysis; Fluorescence polarization spectroscopy; GFP tag; Pull down; Alanine scanning; structure based prediction; Molecular sieving; circular dichroism; Colocalization; Co-IP; Sequence based prediction |
| Interaction ID | 20085 |
| Interacting Domain | Hydrophobic cleft formed by subdomains 1 and 3 |
| Disease Association(s) | Unknown |
| Inhibitor(s) | Unknown |
| Reference(s) | 18025109, 21673315, 20818336, 17588931, 12732141, 19008859 |
| Comments | RPEL motif (61-80) in mouse Myocardin-related transcription factor Mkl1 that binds to the hydrophobic cleft formed by subdomains 1 and 3 of rabbit Alpha-actin-1 |
