|
| Instance ID | 10227 | | Regular Expression | [ED]x{0,2}[ED]x{0,2}[EDQ]x{0,1}[YF]$ | | Motif Instance | EGEEEGEEY | | Bait Uniprot Accession | Q71U36 | | Bait Uniprot Identifier | TBA1A_HUMAN | | Bait Gene Name | TUBA1A | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 443-451 | | Critical Residues | P4; P5; P9 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; NMR; Mutation analysis; SPR | | Interaction ID | 20227 | | Interacting Domain | CAP-Gly domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16954346, 17563362 | | Comments | The C-Terminal acidic tail of Tubulin alpha-1A chain that is responsible for CLIP-170 binding, thus providing a structural basis for the proposed CLIP-170 copolymerization with tubulin on the microtubule plus end |
|
