Instance ID11990
Regular ExpressionEEVD
Motif InstanceEEVD
Bait Uniprot AccessionP11142
Bait Uniprot IdentifierHSP7C_HUMAN
Bait Gene NameHSPA8
Bait OrganismHomo sapiens (Human)
Sequence Position643-646
Critical ResiduesP3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; ITC; SPR; Competition binding
Interaction ID21990
Interacting DomainTetratricopeptide repeat (TPR) domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11877417, 19586912
CommentsThe C-terminal sequence EEVD in human Heat shock cognate 71 kDa protein (HSPA8/HSC70) that binds to the TPR2A domain of human Stress-induced-phosphoprotein 1 (STIP1)/ Hsc70/Hsp90-organizing protein (Hop)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)