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Total : 30 Records
Record No : 1 |
| Instance ID | 10128 | | Regular Expression | FxxF$ | | Motif Instance | FLVF | | Bait Uniprot Accession | Q9LSF1 | | Bait Uniprot Identifier | OXI1_ARATH | | Bait Gene Name | OXI1 | | Sequence Position | 418-421 | | Critical Residues | P1; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP; Mutation analysis | | Interaction ID | 20128 | | Interacting Domain | PIF-binding pocket | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 14749726 | | Comments | "The C-terminal hydrophobic motif in Arabidopsis protein OXI1 (AGC2-1), which acts as a ""docking site"" for recruitment of Arabidopsis PDK1" |
Record No : 2 |
| Instance ID | 10294 | | Regular Expression | [RK]xLx{0,1}[FYLIVMP] | | Motif Instance | RKLAF | | Bait Uniprot Accession | P38826 | | Bait Uniprot Identifier | ORC6_YEAST | | Bait Gene Name | ORC6 | | Sequence Position | 178-182 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20294 | | Interacting Domain | Cyclin, N-terminal domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15105375 | | Comments | Interaction of the S-phase cyclin Clb5 with the RxL motif in the yeast initiator protein Orc6 provides an origin-localized replication control switch |
Record No : 3 |
| Instance ID | 10403 | | Regular Expression | x[FYH]x[IVM][^WFYP][^WFYP][ILM][ILMV]x | | Motif Instance | GFTIDEIMS | | Bait Uniprot Accession | P23803 | | Bait Uniprot Identifier | ODD_DROME | | Bait Gene Name | odd | | Sequence Position | 383-391 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis; Pull down | | Interaction ID | 20403 | | Interacting Domain | WD domain, G-beta repeat | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 16314497 | | Comments | The eh1 motif in Drosophila Protein odd-skipped (odd) that binds to the WD40 domain of the Groucho corepressor |
Record No : 4 |
| Instance ID | 10463 | | Regular Expression | [DE]HxY | | Motif Instance | EHAY | | Bait Uniprot Accession | P06492 | | Bait Uniprot Identifier | VP16_HHV11 | | Bait Gene Name | ORF_Name:UL48 | | Sequence Position | 361-364 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutation analysis | | Interaction ID | 20463 | | Interacting Domain | Galactose oxidase, central domain | | Disease Association(s) | Herpes simplex virus (HSV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 9389645 | | Comments | The herpes simplex virus protein VP16 associates with the endogenous cell-proliferation factor HCF-1 through its HCF-1-binding motif (HBM) |
Record No : 5 |
| Instance ID | 10498 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | QCTLNSLQAMKRRLGSKTT | | Bait Uniprot Accession | Q39575 | | Bait Uniprot Identifier | DYHG_CHLRE | | Bait Gene Name | ODA2 | | Sequence Position | 869-887 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; In-vitro binding assay | | Interaction ID | 20498 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17634291 | | Comments | Ca2+-dependent Interaction of the first EF hand of Chlamydomonas Flagellar outer dynein arm 18 kDa light chain LC4 with the IQ Motif region (869-887) of Dynein gamma chain |
Record No : 6 |
| Instance ID | 10507 | | Regular Expression | xxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx | | Motif Instance | SDNLTRLQVGFKRELIKEV | | Bait Uniprot Accession | Q39575 | | Bait Uniprot Identifier | DYHG_CHLRE | | Bait Gene Name | ODA2 | | Sequence Position | 1157-1175 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Co-IP; In-vitro binding assay | | Interaction ID | 20507 | | Interacting Domain | EF hand | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 17634291 | | Comments | Ca2+-dependent Interaction of the first EF hand of Chlamydomonas Flagellar outer dynein arm 18 kDa light chain LC4 with the IQ Motif region (1157-1175) of Dynein gamma chain |
Record No : 7 |
| Instance ID | 10733 | | Regular Expression | xP[TS]APx | | Motif Instance | RPSAPP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Sequence Position | 95-100 | | Critical Residues | P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Western blot; Co-IP; Mutation analysis | | Interaction ID | 20733 | | Interacting Domain | UEV domain | | Disease Association(s) | Hepatitis E | | Inhibitor(s) | Unknown | | Reference(s) | 21068219 | | Comments | The UEV Domain binding P[TS]AP motif in Protein ORF3 of Hepatitis E virus genotype 1 that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101 |
Record No : 8 |
| Instance ID | 10797 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LRCHE | | Bait Uniprot Accession | O39521 | | Bait Uniprot Identifier | REPA_BEYDV | | Bait Gene Name | ORF_Name:C1 | | Sequence Position | 181-185 | | Critical Residues | P1; P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20797 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10191192 | | Comments | The Rb-binding LxCxE motif in the Bean yellow dwarf virus RepA protein that mediates binding to the maize retinoblastoma protein (ZmRBR1) |
Record No : 9 |
| Instance ID | 10798 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LLCNE | | Bait Uniprot Accession | P14990 | | Bait Uniprot Identifier | REPA_MSVS | | Bait Gene Name | ORF_Name:C1 | | Sequence Position | 198-202 | | Critical Residues | P1; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20798 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15722542 | | Comments | The Rb-binding LxCxE motif in the Maize streak virus RepA protein that mediates binding to the maize retinoblastoma protein (ZmRBR1) |
Record No : 10 |
| Instance ID | 10800 | | Regular Expression | [LI]xCx[DE] | | Motif Instance | LICHE | | Bait Uniprot Accession | P06847 | | Bait Uniprot Identifier | REPA_WDVS | | Bait Gene Name | ORF_Name:C1 | | Sequence Position | 194-198 | | Critical Residues | P3; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Mutation analysis | | Interaction ID | 20800 | | Interacting Domain | B domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 7664747 | | Comments | The Rb-binding LxCxE motif in the Wheat dwarf virus RepA protein that mediates binding to the Human Retinoblastoma-like protein 2 (RBL2) or p130RBR2 |
Record No : 11 |
| Instance ID | 10902 | | Regular Expression | xxx[PV]xxP | | Motif Instance | PHVVDLP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Sequence Position | 102-108 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | PPII helix | | Experimental Method(s) | Mutation analysis; Y2H; Pull down | | Interaction ID | 20902 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11518702 | | Comments | The ORF3 protein of Hepatitis E virus binds to the SH3 domain of human Adapter protein GRB2 through one of its PXXP motifs (102-108) |
Record No : 12 |
| Instance ID | 10903 | | Regular Expression | xxx[PV]xxP | | Motif Instance | PHVVDLP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Sequence Position | 102-108 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | PPII helix | | Experimental Method(s) | Mutation analysis; Y2H; Pull down | | Interaction ID | 20903 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11518702 | | Comments | The ORF3 protein of Hepatitis E virus binds to the SH3 domain of human Proto-oncogene tyrosine-protein kinase SRC through one of its PXXP motifs (102-108) |
Record No : 13 |
| Instance ID | 10908 | | Regular Expression | xxx[PV]xxP | | Motif Instance | VTRPSAP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Sequence Position | 93-99 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | PPII helix | | Experimental Method(s) | Y2H; Pull down; Mutation analysis | | Interaction ID | 20908 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11518702 | | Comments | The ORF3 protein of Hepatitis E virus binds to the SH3 domain of human Adapter protein GRB2 through one of its PXXP motifs (93-99) |
Record No : 14 |
| Instance ID | 10909 | | Regular Expression | xxx[PV]xxP | | Motif Instance | VTRPSAP | | Bait Uniprot Accession | P69616 | | Bait Uniprot Identifier | ORF3_HEVBU | | Bait Gene Name | ORF_Name:ORF3 | | Sequence Position | 93-99 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | PPII helix | | Experimental Method(s) | Y2H; Pull down; Mutation analysis | | Interaction ID | 20909 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11518702 | | Comments | The ORF3 protein of Hepatitis E virus binds to the SH3 domain of human Proto-oncogene tyrosine-protein kinase SRC through one of its PXXP motifs (93-99) |
Record No : 15 |
| Instance ID | 11054 | | Regular Expression | PPxY | | Motif Instance | PPSY | | Bait Uniprot Accession | P03276 | | Bait Uniprot Identifier | CAPSP_ADE02 | | Bait Gene Name | ORF_Name:L2 | | Sequence Position | 12-15 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Far Western blotting; Co-IP; SPR; Mutation analysis | | Interaction ID | 21054 | | Interacting Domain | WW domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12450395 | | Comments | The PY motif of the Penton base protein of Human adenovirus 2 that binds to the WW domain of human NEDD4-like E3 ubiquitin-protein ligase WWP1 |
Record No : 16 |
| Instance ID | 11278 | | Regular Expression | [KR]xTQTx | | Motif Instance | KSTQTV | | Bait Uniprot Accession | P09569 | | Bait Uniprot Identifier | PRO_ADE12 | | Bait Gene Name | ORF_Name:L3 | | Sequence Position | 109-114 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay | | Interaction ID | 21278 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12782328 | | Comments | The LC8 dynein light chain binding motif in Human adenovirus A serotype 12 Endoprotease that binds to the rat 8 kDa Dynein light chain 1 (Dynll1) |
Record No : 17 |
| Instance ID | 11279 | | Regular Expression | [KR]xTQTx | | Motif Instance | KSTQTV | | Bait Uniprot Accession | P11825 | | Bait Uniprot Identifier | PRO_ADE40 | | Bait Gene Name | ORF_Name:L3 | | Sequence Position | 109-114 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay | | Interaction ID | 21279 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12782328 | | Comments | The LC8 dynein light chain binding motif in Human adenovirus F serotype 40 Endoprotease that binds to the rat 8 kDa Dynein light chain 1 (Dynll1) |
Record No : 18 |
| Instance ID | 11280 | | Regular Expression | [KR]xTQTx | | Motif Instance | KSTQTV | | Bait Uniprot Accession | P11826 | | Bait Uniprot Identifier | PRO_ADE41 | | Bait Gene Name | ORF_Name:L3 | | Sequence Position | 109-114 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay | | Interaction ID | 21280 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12782328 | | Comments | The LC8 dynein light chain binding motif in Human adenovirus F serotype 41 Endoprotease that binds to the rat 8 kDa Dynein light chain 1 (Dynll1) |
Record No : 19 |
| Instance ID | 11320 | | Regular Expression | [DS]Kx[TVI]Q[TV][DE] | | Motif Instance | AKSTQTF | | Bait Uniprot Accession | P10193 | | Bait Uniprot Identifier | OBP_HHV11 | | Bait Gene Name | ORF_Name:UL9 | | Sequence Position | 745-751 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay | | Interaction ID | 21320 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21533121 | | Comments | The LC8 dynein light chain binding motif in Replication origin-binding protein UL9 of Human herpes simplex virus 1 that interacts with the human 8 kDa Dynein light chain 1 (DYNLL1/DLC8) |
Record No : 20 |
| Instance ID | 11321 | | Regular Expression | [DS]Kx[TVI]Q[TV][DE] | | Motif Instance | AKSTQTF | | Bait Uniprot Accession | P10193 | | Bait Uniprot Identifier | OBP_HHV11 | | Bait Gene Name | ORF_Name:UL9 | | Sequence Position | 745-751 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay | | Interaction ID | 21321 | | Interacting Domain | Unknown | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 21533121 | | Comments | The LC8 dynein light chain binding motif in Replication origin-binding protein UL9 of Human herpes simplex virus 1 that interacts with the human 8 kDa Dynein light chain 2 (DYNLL2/DLC2) |
Record No : 21 |
| Instance ID | 11828 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RSTSL | | Bait Uniprot Accession | C8ZAV3 | | Bait Uniprot Identifier | C8ZAV3_YEAS8 | | Bait Gene Name | ORF_Name:EC1118_1I12 | | Sequence Position | 645-649 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21828 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Bnr1p of Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 22 |
| Instance ID | 11829 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RTSSL | | Bait Uniprot Accession | C8Z519 | | Bait Uniprot Identifier | C8Z519_YEAS8 | | Bait Gene Name | ORF_Name:EC1118_1D0_ | | Sequence Position | 117-121 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21829 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Ste5p of Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 23 |
| Instance ID | 11832 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RSTSL | | Bait Uniprot Accession | N1P0Y3 | | Bait Uniprot Identifier | N1P0Y3_YEASC | | Bait Gene Name | ORF_Name:CENPK1137D_ | | Sequence Position | 645-649 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21832 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Bnr1p of Saccharomyces cerevisiae (strain CEN.PK113-7D) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 24 |
| Instance ID | 11833 | | Regular Expression | R[ST][ST]SL | | Motif Instance | RTSSL | | Bait Uniprot Accession | N1P866 | | Bait Uniprot Identifier | N1P866_YEASC | | Bait Gene Name | ORF_Name:CENPK1137D_ | | Sequence Position | 117-121 | | Critical Residues | P1; P2; P4; P5 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Peptide binding assay; Mutational analysis | | Interaction ID | 21833 | | Interacting Domain | SH3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 18280496 | | Comments | The consensus R[ST][ST]SL motif in Ste5p of Saccharomyces cerevisiae (strain CEN.PK113-7D) that is necessary, but not sufficient for binding to the Fus1p SH3 domain |
Record No : 25 |
| Instance ID | 12018 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation analysis; Pull down(GST tag) | | Interaction ID | 22018 | | Interacting Domain | PDZ domain | | Disease Association(s) | Shigellosis | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 7 (PDLIM7/ENIGMA), leading to activation of isoforms of protein kinase C (PKC) |
Record No : 26 |
| Instance ID | 12019 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJW6 | | Bait Uniprot Identifier | Q9AJW6_SHIFL | | Bait Gene Name | ospE2 | | Sequence Position | 83-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Pull down(GST tag) | | Interaction ID | 22019 | | Interacting Domain | PDZ domain | | Disease Association(s) | Shigellosis | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE2 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 7 (PDLIM7/ENIGMA) |
Record No : 27 |
| Instance ID | 12020 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Fluorescence polarization | | Interaction ID | 22020 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human PDZ and LIM domain protein 3 (PDLIM3) |
Record No : 28 |
| Instance ID | 12021 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | QRYSDF | | Bait Uniprot Accession | Q9AJU4 | | Bait Uniprot Identifier | Q9AJU4_SHIFL | | Bait Gene Name | ospE1 | | Sequence Position | 86-88 | | Critical Residues | P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Sequence based prediction; Fluorescence polarization | | Interaction ID | 22021 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 25124035 | | Comments | C-terminal class 1 PDZ-binding motif in the effector protein OspE1 of Shigella flexneri serotype 2a strain 2457T that mediates its interaction with human MAGI1 |
Record No : 29 |
| Instance ID | 12040 | | Regular Expression | RGD | | Motif Instance | RGD | | Bait Uniprot Accession | Q77UU3 | | Bait Uniprot Identifier | Q77UU3_HHV8 | | Bait Gene Name | ORF8 | | Sequence Position | 27-29 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Sequence based prediction; Competition binding | | Interaction ID | 22040 | | Interacting Domain | N-terminal Integrin beta subunit | | Disease Association(s) | Kaposi's sarcoma | | Inhibitor(s) | Unknown | | Reference(s) | 12584338, 24814923 | | Comments | Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma-associated herpesvirus envelope glycoprotein B binds beta 1 integrin via its RGD motif, which may play roles in the infection of target cells and in Kaposi's sarcoma pathogenesis |
Record No : 30 |
| Instance ID | 12054 | | Regular Expression | [DE][DE][ILVM]Yx | | Motif Instance | EDMYR | | Bait Uniprot Accession | Q96BN8 | | Bait Uniprot Identifier | OTUL_HUMAN | | Bait Gene Name | OTULIN | | Sequence Position | 53-57 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Tyr-P4 | | Secondary Structure | Coil | | Experimental Method(s) | X-ray crystallography; ITC; Mutation analysis; Co-IP; Pull down(GST tag) | | Interaction ID | 22054 | | Interacting Domain | PUB domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 24726327 | | Comments | The PUB interacting motif (PIM) of human Ubiquitin thioesterase OTULIN that binds to the PUB domain of human E3 ubiquitin-protein ligase RNF31/HOIP |
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