|
Total : 15 Records
Record No : 1 |
| Instance ID | 10024 | | Regular Expression | Rx[^P]([ST])[^P]P | | Motif Instance | RAHSSP | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Sequence Position | 124-129 | | Critical Residues | P4 | | Motif PTM(s) | Phosphorylation at Ser-P4 | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP; Mutation analysis; Pull down | | Interaction ID | 20024 | | Interacting Domain | 14-3-3 domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 12535517, 17974916 | | Comments | Akt phosphorylates the Yes-associated protein, at serine 127, to induce interaction with 14-3-3 protein tau and attenuation of p73-mediated apoptosis |
Record No : 2 |
| Instance ID | 10339 | | Regular Expression | xNPFx | | Motif Instance | NNPFV | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Sequence Position | 362-366 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Pull down; Co-IP | | Interaction ID | 20339 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (362-366) of YAP1801 |
Record No : 3 |
| Instance ID | 10349 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Sequence Position | 479-483 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20349 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (479-483) of YAP1801 |
Record No : 4 |
| Instance ID | 10354 | | Regular Expression | xNPFx | | Motif Instance | YNPFG | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Sequence Position | 339-343 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20354 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (339-343) of YAP1802 |
Record No : 5 |
| Instance ID | 10362 | | Regular Expression | xNPFx | | Motif Instance | NNPFS | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Sequence Position | 452-456 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20362 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (452-456) of YAP1802 |
Record No : 6 |
| Instance ID | 10365 | | Regular Expression | xNPFx | | Motif Instance | GNPFQ | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Sequence Position | 493-497 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20365 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (493-497) of YAP1802 |
Record No : 7 |
| Instance ID | 10370 | | Regular Expression | xNPFx | | Motif Instance | YNPFG | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Sequence Position | 336-340 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Co-IP | | Interaction ID | 20370 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (336-340) of YAP1801 |
Record No : 8 |
| Instance ID | 10372 | | Regular Expression | xNPFx | | Motif Instance | NNPFA | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Sequence Position | 456-460 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20372 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (456-460) of YAP1801 |
Record No : 9 |
| Instance ID | 10373 | | Regular Expression | xNPFx | | Motif Instance | SNPFQ | | Bait Uniprot Accession | P38856 | | Bait Uniprot Identifier | AP18A_YEAST | | Bait Gene Name | YAP1801 | | Sequence Position | 502-506 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H; Pull down; Co-IP | | Interaction ID | 20373 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1801, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (502-506) of YAP1801 |
Record No : 10 |
| Instance ID | 10374 | | Regular Expression | xNPFx | | Motif Instance | ANPFL | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Sequence Position | 372-376 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20374 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (372-376) of YAP1802 |
Record No : 11 |
| Instance ID | 10375 | | Regular Expression | xNPFx | | Motif Instance | PNPFT | | Bait Uniprot Accession | P53309 | | Bait Uniprot Identifier | AP18B_YEAST | | Bait Gene Name | YAP1802 | | Sequence Position | 473-477 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Y2H | | Interaction ID | 20375 | | Interacting Domain | EH domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 9531549, 11940605 | | Comments | EH domain-dependent interaction between PAN1, yeast eps15, and YAP1802, one of two yeast homologues of a class of clathrin assembly proteins (AP180) through the NPF motif (473-477) of YAP1802 |
Record No : 12 |
| Instance ID | 10655 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Sequence Position | 483-488 | | Critical Residues | Unknown | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | ITC; Pull down; Co-IP; Colocalization; Mutation analysis | | Interaction ID | 20655 | | Interacting Domain | PDZ domain | | Disease Association(s) | Cancer | | Inhibitor(s) | Unknown | | Reference(s) | 20868367 | | Comments | Class 1 PDZ-binding motif (483-488) in human YAP1 (Yes kinase-associated protein 1) that binds to the first PDZ domain of Tight junction protein ZO-2 (TJP2) |
Record No : 13 |
| Instance ID | 10657 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Sequence Position | 499-504 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Mutation disrupting interaction; Peptide binding to perpetrator; Pull down; Co-IP; Colocalization; Competition binding; Mutation analysis | | Interaction ID | 20657 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10562288 | | Comments | C-terminal class 1 PDZ-binding motif (499-504) in human Cystic fibrosis transmembrane conductance regulator (CFTR) that mediates binding to the PDZ domain of Na(+)/H(+) exchange regulatory cofactor NHERF1/EBP50 (SLC9A3R1) |
Record No : 14 |
| Instance ID | 10658 | | Regular Expression | xxx[ST]x[ACVILF]$ | | Motif Instance | SFLTWL | | Bait Uniprot Accession | P46937 | | Bait Uniprot Identifier | YAP1_HUMAN | | Bait Gene Name | YAP1 | | Sequence Position | 449-454 | | Critical Residues | P3; P4; P5; P6 | | Motif PTM(s) | Unknown | | Secondary Structure | Disordered | | Experimental Method(s) | Pull down; Co-IP; Competition binding; Mutation analysis | | Interaction ID | 20658 | | Interacting Domain | PDZ domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 10562288 | | Comments | Class 1 PDZ-binding motif (449-454) in human Cystic fibrosis transmembrane conductance regulator (CFTR) that mediates binding to the PDZ domain of Na(+)/H(+) exchange regulatory cofactor NHERF1/EBP50 (SLC9A3R1) |
Record No : 15 |
| Instance ID | 11865 | | Regular Expression | HxPR | | Motif Instance | HGPR | | Bait Uniprot Accession | P25490 | | Bait Uniprot Identifier | TYY1_HUMAN | | Bait Gene Name | YY1 | | Sequence Position | 320-323 | | Critical Residues | P1; P3; P4 | | Motif PTM(s) | Unknown | | Secondary Structure | Unknown | | Experimental Method(s) | Mutational analysis | | Interaction ID | 21865 | | Interacting Domain | Carboxyl-flanking region of the SPXX region | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 15720400 | | Comments | CP2-binding HXPR motif of Transcriptional repressor protein Yin-Yang1 (YY1) that is involved in interactions with the transcriptional factor CP2 |
|
